| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Karate Kid | $33,274 | - | 12 | - | $2,772 | $39,162 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Salt | $17,242 | -52.9% | 10 | - | $1,724 | $139,718 | 3 | Sony Pictures Releasing | false | false |
| 3 | 3 | Toy Story 3 | $12,792 | -34.9% | 13 | - | $984 | $138,949 | 4 | Walt Disney Pictures | false | false |
| 4 | 4 | Marmaduke | $12,067 | -36% | 8 | - | $1,508 | $79,486 | 3 | 20th Century Fox International | false | false |
| 5 | 2 | The Expendables | $10,295 | -53.4% | 6 | - | $1,715 | $94,048 | 3 | N/A | false | false |
| 6 | 6 | Inception | $8,544 | -32.7% | 10 | - | $854 | $339,300 | 7 | Warner Bros. | false | false |
| 7 | 5 | Cats & Dogs: The Revenge of Kitty Galore | $8,159 | -44.3% | 11 | - | $741 | $38,585 | 2 | Warner Bros. | false | false |
| 8 | - | Machete | $7,080 | - | 4 | - | $1,770 | $8,629 | 1 | N/A | true | false |
| 9 | 7 | Get Him to the Greek | $6,878 | -42.5% | 9 | - | $764 | $125,813 | 5 | United International Pictures | false | false |
| 10 | 10 | The Kings of Mykonos | $5,256 | -30.4% | 3 | - | $1,752 | $18,313 | 2 | N/A | false | false |
| 11 | 9 | The Last Airbender | $4,359 | -52.7% | 17 | - | $256 | $173,714 | 5 | United International Pictures | false | false |
| 12 | 8 | Knight and Day 2010 Re-release | $4,296 | -56.9% | 12 | - | $358 | $230,562 | 6 | 20th Century Fox International | false | false |
| 13 | 11 | Grown Ups | $2,723 | -63.6% | 7 | - | $389 | $251,066 | 8 | Sony Pictures Releasing | false | false |
| 14 | 13 | Mother and Child | $2,550 | -40.7% | 5 | - | $510 | $14,424 | 2 | United International Pictures | false | false |
| 15 | 12 | The A-Team | $2,507 | -60.7% | 7 | - | $358 | $53,110 | 4 | 20th Century Fox International | false | false |
