| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Karate Kid | $20,037 | -39.8% | 12 | - | $1,669 | $68,407 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Going the Distance | $13,950 | - | 7 | - | $1,992 | $15,384 | 1 | Warner Bros. | true | false |
| 3 | 2 | Salt | $10,229 | -40.7% | 10 | - | $1,022 | $155,249 | 4 | Sony Pictures Releasing | false | false |
| 4 | 4 | Marmaduke | $7,667 | -36.5% | 8 | - | $958 | $91,218 | 4 | 20th Century Fox International | false | false |
| 5 | 3 | Toy Story 3 | $7,536 | -41.1% | 13 | - | $579 | $153,252 | 5 | Walt Disney Pictures | false | false |
| 6 | - | Charlie St. Cloud | $6,544 | - | 8 | - | $818 | $8,592 | 1 | United International Pictures | true | false |
| 7 | 6 | Inception | $5,783 | -32.3% | 10 | - | $578 | $358,652 | 8 | Warner Bros. | false | false |
| 8 | 5 | The Expendables | $4,931 | -52.1% | 6 | - | $821 | $104,065 | 4 | N/A | false | false |
| 9 | 8 | Machete | $4,746 | -33% | 4 | - | $1,186 | $19,033 | 2 | N/A | false | false |
| 10 | - | Resident Evil: Afterlife | $4,686 | - | 8 | - | $585 | $4,686 | 1 | Sony Pictures Releasing | true | false |
| 11 | 9 | Get Him to the Greek | $4,418 | -35.8% | 9 | - | $490 | $133,501 | 6 | United International Pictures | false | false |
| 12 | 7 | Cats & Dogs: The Revenge of Kitty Galore | $4,415 | -45.9% | 11 | - | $401 | $45,597 | 3 | Warner Bros. | false | false |
| 13 | 10 | The Kings of Mykonos | $2,632 | -49.9% | 3 | - | $877 | $23,341 | 3 | N/A | false | false |
| 14 | 11 | The Last Airbender | $1,732 | -60.3% | 17 | - | $101 | $179,326 | 6 | United International Pictures | false | false |
| 15 | 14 | Mother and Child | $1,637 | -35.8% | 5 | - | $327 | $18,531 | 3 | United International Pictures | false | false |
| 16 | 15 | The A-Team | $1,337 | -46.7% | 7 | - | $191 | $58,921 | 5 | 20th Century Fox International | false | false |
