| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Secret Spell | $92,255 | - | 14 | - | $6,589 | $92,255 | 1 | N/A | true | false |
| 2 | 1 | Despicable Me | $30,219 | -28.5% | 15 | +1 | $2,014 | $92,601 | 2 | United International Pictures | false | false |
| 3 | 2 | The Other Guys | $21,962 | -40.7% | 5 | -1 | $4,392 | $85,660 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | Step Up 3D | $8,890 | -59.5% | 3 | -2 | $2,963 | $96,326 | 3 | N/A | false | false |
| 5 | 4 | The Expendables | $5,915 | -55.8% | 4 | - | $1,478 | $234,418 | 4 | N/A | false | false |
| 6 | 5 | The Ghost Writer | $5,065 | -27.6% | 3 | - | $1,688 | $19,801 | 2 | N/A | false | false |
| 7 | 7 | Scott Pilgrim vs. the World | $3,126 | -52% | 2 | -1 | $1,563 | $50,313 | 3 | United International Pictures | false | false |
| 8 | - | Remember Me | $2,811 | - | 2 | - | $1,405 | $2,811 | 1 | N/A | true | false |
| 9 | 8 | Inception | $2,615 | -44.9% | 3 | - | $871 | $464,021 | 8 | Warner Bros. | false | false |
| 10 | 10 | Letters to Juliet | $2,346 | -29.5% | 1 | - | $2,346 | $47,087 | 4 | N/A | false | false |
| 11 | 9 | Salt | $1,349 | -67.2% | 2 | -1 | $674 | $175,440 | 5 | Sony Pictures Releasing | false | false |
| 12 | 6 | Cats & Dogs: The Revenge of Kitty Galore | $1,238 | -81.2% | 5 | +1 | $247 | $49,946 | 4 | Warner Bros. | false | false |
| 13 | 12 | Toy Story 3 | $927 | -46.9% | 2 | -1 | $463 | $420,970 | 13 | Walt Disney Pictures | false | false |
| 14 | 14 | The Human Centipede (First Sequence) | $731 | -41.4% | 1 | - | $731 | $9,632 | 3 | N/A | false | false |
| 15 | 11 | Shrek Forever After | $548 | -71.4% | 2 | -1 | $274 | $289,877 | 9 | United International Pictures | false | false |
| 16 | - | Resident Evil: Afterlife | $473 | - | 1 | - | $473 | $473 | 1 | Sony Pictures Releasing | true | false |
| 17 | 15 | The Karate Kid | $466 | -54.4% | 1 | - | $466 | $136,567 | 7 | Sony Pictures Releasing | false | false |
| 18 | 16 | Vampires Suck | $149 | -83.9% | 1 | -1 | $149 | $21,865 | 4 | 20th Century Fox International | false | false |
| 19 | 13 | The Last Airbender | $76 | -94.5% | 1 | -1 | $76 | $58,996 | 5 | United International Pictures | false | false |
