| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Resident Evil: Afterlife | $394,920 | -61.8% | 58 | -1 | $6,808 | $1,706,419 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Devil | $276,266 | - | 25 | - | $11,050 | $276,266 | 1 | United International Pictures | true | false |
| 3 | - | The Shock Labyrinth 3D | $110,071 | - | 14 | - | $7,862 | $110,071 | 1 | Cathay-Keris Films | true | false |
| 4 | 3 | Grown Ups | $62,396 | -55.8% | 18 | -8 | $3,466 | $962,290 | 4 | Sony Pictures Releasing | false | false |
| 5 | 4 | Going the Distance | $51,190 | -58.1% | 18 | -5 | $2,843 | $398,894 | 3 | Warner Bros. | false | false |
| 6 | 2 | Cats & Dogs: The Revenge of Kitty Galore | $39,890 | -80% | 22 | -13 | $1,813 | $574,939 | 3 | Golden Village Pictures | false | false |
| 7 | - | Alpha and Omega | $35,601 | - | 14 | - | $2,542 | $35,601 | 1 | Shaw Organisation | true | false |
| 8 | - | The Infidel | $29,578 | - | 2 | - | $14,789 | $37,121 | 1 | Cathay-Keris Films | true | false |
| 9 | - | The Girl Who Played with Fire | $28,237 | - | 4 | - | $7,059 | $28,237 | 1 | Golden Village Pictures | true | false |
| 10 | 6 | Step Up 3D | $27,028 | -70.1% | 8 | -17 | $3,378 | $1,712,496 | 5 | Shaw Organisation | false | false |
| 11 | 8 | Love Cuts | $22,277 | -57.8% | 18 | - | $1,237 | $104,820 | 2 | Golden Village Pictures | false | false |
| 12 | 5 | Haunted Changi | $22,143 | -75.6% | 18 | -4 | $1,230 | $404,429 | 3 | Golden Village Pictures | false | false |
| 13 | - | I Love You Too | $14,557 | - | 4 | - | $3,639 | $14,557 | 1 | Golden Village Pictures | true | false |
| 14 | 11 | Girl$ | $11,588 | -54.9% | 3 | -2 | $3,862 | $86,511 | 3 | Shaw Organisation | false | false |
| 15 | - | My Darling Is a Foreigner | $11,389 | - | 2 | - | $5,694 | $11,389 | 1 | Golden Village Pictures | true | false |
| 16 | 12 | Inception | $9,647 | -52.7% | 3 | -3 | $3,215 | $3,974,786 | 10 | Warner Bros. | false | false |
| 17 | 7 | Vampires Suck | $7,991 | -86.8% | 11 | -12 | $726 | $267,563 | 3 | 20th Century Fox International | false | false |
| 18 | 9 | The Expendables | $7,174 | -85.1% | 3 | -16 | $2,391 | $1,371,833 | 5 | Cathay-Keris Films | false | false |
| 19 | 14 | Heartbreaker | $6,963 | -43.1% | 1 | -1 | $6,963 | $85,533 | 4 | Cathay-Keris Films | false | false |
| 20 | 15 | Babies | $6,203 | -40.8% | 1 | - | $6,203 | $18,962 | 2 | Shaw Organisation | false | false |
| 21 | 24 | The Girl with the Dragon Tattoo | $6,032 | +532.9% | 2 | -1 | $3,016 | $124,156 | 6 | Golden Village Pictures | false | false |
| 22 | 13 | Avatar 2010 Special Edition | $5,645 | -72.2% | 4 | -1 | $1,411 | $153,794 | 4 | 20th Century Fox International | false | false |
| 23 | 10 | The Hole | $3,006 | -88.9% | 8 | -8 | $375 | $91,712 | 3 | Shaw Organisation | false | false |
| 24 | 18 | Villon's Wife | $2,830 | -54.5% | 1 | - | $2,830 | $17,150 | 3 | Cathay-Keris Films | false | false |
| 25 | 17 | The Stool Pigeon | $869 | -87% | 2 | -5 | $434 | $145,960 | 4 | Golden Village Pictures | false | false |
| 26 | 19 | Aftershock | $662 | -81.2% | 2 | - | $331 | $598,718 | 8 | Golden Village Pictures | false | false |
| 27 | 20 | Despicable Me | $457 | -83.2% | 1 | - | $457 | $2,914,329 | 11 | United International Pictures | false | false |
| 28 | 22 | The Last Airbender | $426 | -79.7% | 1 | -1 | $426 | $1,964,404 | 7 | United International Pictures | false | false |
