| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Sorcerer's Apprentice | $27,687 | - | 10 | - | $2,768 | $33,182 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Dinner for Schmucks | $26,185 | - | 8 | - | $3,273 | $30,078 | 1 | United International Pictures | true | false |
| 3 | 10 | Resident Evil: Afterlife | $21,900 | +367.3% | 17 | +9 | $1,288 | $52,073 | 2 | Sony Pictures Releasing | false | false |
| 4 | 5 | Toy Story 3 | $18,500 | +145.5% | 13 | - | $1,423 | $174,305 | 6 | Walt Disney Pictures | false | false |
| 5 | 1 | The Karate Kid | $18,125 | -9.5% | 12 | - | $1,510 | $91,289 | 3 | Sony Pictures Releasing | false | false |
| 6 | 2 | Going the Distance | $13,584 | -2.6% | 7 | - | $1,940 | $38,668 | 2 | Warner Bros. | false | false |
| 7 | 4 | Marmaduke | $11,602 | +51.3% | 8 | - | $1,450 | $105,089 | 5 | 20th Century Fox International | false | false |
| 8 | 12 | Cats & Dogs: The Revenge of Kitty Galore | $8,460 | +91.6% | 11 | - | $769 | $55,305 | 4 | Warner Bros. | false | false |
| 9 | 3 | Salt | $7,676 | -25% | 10 | - | $767 | $165,701 | 5 | Sony Pictures Releasing | false | false |
| 10 | 9 | Machete | $6,257 | +31.8% | 4 | - | $1,564 | $29,312 | 3 | N/A | false | false |
| 11 | 6 | Charlie St. Cloud | $5,166 | -21.1% | 8 | - | $645 | $17,147 | 2 | United International Pictures | false | false |
| 12 | 8 | The Expendables | $5,044 | +2.3% | 6 | - | $840 | $111,251 | 5 | N/A | false | false |
| 13 | 11 | Get Him to the Greek | $2,972 | -32.7% | 9 | - | $330 | $140,899 | 7 | United International Pictures | false | false |
| 14 | 13 | The Kings of Mykonos | $2,704 | +2.7% | 3 | - | $901 | $27,236 | 4 | N/A | false | false |
