| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Despicable Me | $319,519 | - | 112 | - | $2,852 | $335,851 | 1 | United International Pictures | true | false |
| 2 | - | Truth About Men | $262,660 | - | 37 | - | $7,098 | $314,912 | 1 | Nordisk Film | true | false |
| 3 | 1 | Wall Street: Money Never Sleeps | $248,237 | -26.6% | 58 | - | $4,279 | $1,042,759 | 2 | 20th Century Fox International | false | false |
| 4 | - | Piranha 3D | $183,535 | - | 49 | - | $3,745 | $183,535 | 5 | United International Pictures | false | false |
| 5 | 2 | In a Better World | $165,007 | -37.3% | 59 | -12 | $2,796 | $3,916,777 | 7 | Nordisk Film | false | false |
| 6 | 4 | Grown Ups | $144,173 | -34.9% | 30 | - | $4,805 | $444,105 | 2 | Sony Pictures Releasing | false | false |
| 7 | 3 | Toy Story 3 | $121,333 | -51.4% | 120 | -22 | $1,011 | $4,725,338 | 7 | Walt Disney Pictures | false | false |
| 8 | 6 | Inception | $70,472 | -33.8% | 23 | -18 | $3,064 | $7,393,988 | 11 | Sandrew Metronome Distribution Sverige AB | false | false |
| 9 | - | Buried | $59,159 | - | 14 | - | $4,225 | $70,902 | 1 | Scanbox Entertainment | true | false |
| 10 | 5 | Resident Evil: Afterlife | $52,335 | -66.6% | 37 | -11 | $1,414 | $580,346 | 3 | Sony Pictures Releasing | false | false |
| 11 | 7 | A Turtle's Tale: Sammy's Adventures | $31,892 | -64.6% | 45 | -10 | $708 | $431,182 | 4 | Filmcompagniet | false | false |
| 12 | 8 | Salt | $30,459 | -58.4% | 30 | -13 | $1,015 | $947,867 | 5 | Sony Pictures Releasing | false | false |
| 13 | 9 | The Kids Are All Right | $25,117 | -40.4% | 11 | -1 | $2,283 | $289,249 | 4 | Scanbox Entertainment | false | false |
| 14 | 12 | The Experiment 2010 Re-release | $15,860 | -27.2% | 9 | -9 | $1,762 | $295,722 | 5 | Sandrew Metronome Distribution Sverige AB | false | false |
| 15 | 19 | Fish Tank | $11,198 | -8.1% | 4 | - | $2,799 | $33,432 | 2 | Camera Film | false | false |
| 16 | 13 | Shrek Forever After | $10,576 | -51.1% | 21 | -2 | $503 | $5,480,606 | 14 | United International Pictures | false | false |
| 17 | 14 | Marmaduke | $8,248 | -52.6% | 14 | -7 | $589 | $922,641 | 11 | 20th Century Fox International | false | false |
| 18 | - | Four Lions | $8,066 | - | 1 | - | $8,066 | $8,645 | 1 | Miracle Films | true | false |
| 19 | 18 | The Expendables | $7,017 | -43.7% | 17 | -4 | $412 | $1,520,584 | 9 | United International Pictures | false | false |
| 20 | 15 | The Karate Kid | $791 | -95% | 4 | -11 | $197 | $1,336,058 | 10 | Sony Pictures Releasing | false | false |
