| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Eat Pray Love | $35,895 | -14.5% | 6 | - | $5,982 | $100,580 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | The Last Airbender | $21,661 | -16.3% | 8 | - | $2,707 | $56,767 | 2 | Paramount Pictures International | false | false |
| 3 | 3 | Grown Ups | $18,257 | -5.7% | 7 | -1 | $2,608 | $144,346 | 4 | Sony Pictures Releasing | false | false |
| 4 | - | Legend of the Guardians: The Owls of Ga'Hoole | $14,458 | - | 8 | - | $1,807 | $14,458 | 1 | Warner Bros. | true | false |
| 5 | - | Solitary Man | $14,367 | - | 4 | - | $3,591 | $14,367 | 1 | N/A | true | false |
| 6 | - | Predators | $11,643 | - | 5 | - | $2,328 | $11,643 | 1 | 20th Century Fox International | true | false |
| 7 | 4 | Wall Street: Money Never Sleeps | $11,151 | -15.2% | 6 | -1 | $1,858 | $59,553 | 3 | 20th Century Fox International | false | false |
| 8 | 5 | Igualita a mí | $10,011 | -19.4% | 4 | -2 | $2,502 | $131,197 | 5 | Walt Disney Pictures | false | false |
| 9 | 7 | Nanny McPhee Returns | $4,868 | -3.8% | 5 | - | $973 | $22,901 | 3 | Universal Pictures International (UPI) | false | false |
| 10 | 10 | Inception | $3,417 | -5.8% | 2 | -1 | $1,708 | $277,920 | 11 | Warner Bros. | false | false |
| 11 | 9 | Norberto's Deadline | $3,056 | -20.6% | 3 | - | $1,018 | $8,122 | 2 | N/A | false | false |
| 12 | - | Life as We Know It | $3,045 | - | 1 | - | $3,045 | $3,045 | - | Warner Bros. | - | false |
| 13 | 14 | Nora's Will | $2,410 | +23.9% | 1 | - | $2,410 | $6,881 | 3 | N/A | false | false |
| 14 | 6 | Resident Evil: Afterlife | $2,080 | -76% | 3 | -2 | $693 | $158,321 | 5 | Sony Pictures Releasing | false | false |
| 15 | - | Hachi: A Dog's Tale | $2,017 | - | 2 | - | $1,008 | $2,017 | - | N/A | - | false |
| 16 | 13 | Tinker Bell and the Great Fairy Rescue | $1,813 | -21.2% | 4 | -1 | $453 | $43,991 | 5 | Walt Disney Pictures | false | false |
| 17 | 11 | Vincere | $1,615 | -48.2% | 1 | -1 | $1,615 | $11,708 | 3 | N/A | false | false |
| 18 | 15 | Seraphine | $1,175 | -24.2% | 1 | - | $1,175 | $19,024 | 6 | N/A | false | false |
| 19 | 18 | Little Girl | $856 | -20.2% | 1 | - | $856 | $3,296 | 3 | N/A | false | false |
| 20 | 8 | Going the Distance | $575 | -87.5% | 2 | -2 | $287 | $32,988 | 4 | Warner Bros. | false | false |
| 21 | - | In Your Name | $504 | - | 1 | - | $504 | $504 | 1 | N/A | true | false |
| 22 | 16 | The Sorcerer's Apprentice | $408 | -69.7% | 1 | -1 | $408 | $71,529 | 7 | Walt Disney Pictures | false | false |
| 23 | 12 | Cats & Dogs: The Revenge of Kitty Galore | $361 | -88.1% | 2 | -4 | $180 | $189,072 | 8 | Warner Bros. | false | false |
| 24 | 26 | Despicable Me | $190 | +16.6% | 1 | -1 | $190 | $159,438 | 11 | Universal Pictures International (UPI) | false | false |
| 25 | 22 | Furry Vengeance | $165 | -51.9% | 2 | - | $82 | $12,204 | 4 | N/A | false | false |
| 26 | 27 | Salt | $156 | +9.9% | 1 | - | $156 | $94,492 | 9 | Sony Pictures Releasing | false | false |
| 27 | 23 | Five Minutes of Heaven | $138 | -57.7% | 1 | - | $138 | $5,224 | 4 | N/A | false | false |
| 28 | - | Pax Americana and the Weaponization of Space | $128 | - | 1 | - | $128 | $128 | 1 | N/A | true | false |
| 29 | 17 | A Single Man | $104 | -90.5% | 1 | -1 | $104 | $9,975 | 4 | N/A | false | false |
| 30 | 28 | Birds of Paradise | $64 | -47.5% | 1 | -1 | $64 | $3,664 | 4 | N/A | false | false |
