| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Legend of the Guardians: The Owls of Ga'Hoole | $320,728 | - | 87 | - | $3,686 | $367,675 | 1 | Warner Bros. | true | false |
| 2 | 1 | Eat Pray Love | $253,952 | -37.8% | 40 | - | $6,348 | $747,983 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | Vampires Suck | $224,113 | -23.1% | 41 | - | $5,466 | $540,931 | 2 | 20th Century Fox International | false | false |
| 4 | 4 | The Town | $161,880 | -9% | 25 | - | $6,475 | $729,762 | 3 | Warner Bros. | false | false |
| 5 | 5 | Wall Street: Money Never Sleeps | $147,844 | -12.6% | 43 | - | $3,438 | $1,018,741 | 4 | 20th Century Fox International | false | false |
| 6 | 3 | Resident Evil: Afterlife | $144,062 | -31.1% | 35 | - | $4,116 | $752,263 | 3 | Belga Films | false | false |
| 7 | - | Sarah's Key | $98,148 | - | 22 | - | $4,461 | $103,286 | 1 | Benelux Film Distributors | true | false |
| 8 | 9 | Of Gods and Men | $81,222 | +20.2% | 26 | +4 | $3,123 | $820,687 | 6 | Benelux Film Distributors | false | false |
| 9 | 7 | Grown Ups | $69,458 | -7.7% | 24 | -1 | $2,894 | $816,525 | 6 | Sony Pictures Releasing | false | false |
| 10 | 6 | Inception | $68,790 | -16.6% | 32 | -7 | $2,149 | $5,937,944 | 13 | Warner Bros. | false | false |
| 11 | 8 | Oxygen | $57,093 | -23.3% | 22 | -1 | $2,595 | $712,778 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 12 | 10 | Turquaze | $50,163 | -9.8% | 9 | - | $5,573 | $199,190 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 13 | 15 | A Turtle's Tale: Sammy's Adventures | $45,691 | +17.7% | 37 | -8 | $1,234 | $1,974,878 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 14 | 13 | Marmaduke | $45,381 | +9.8% | 41 | - | $1,106 | $1,173,598 | 9 | 20th Century Fox International | false | false |
| 15 | 14 | I Am Love | $41,088 | +1.7% | 10 | - | $4,108 | $183,064 | 3 | Cinéart | false | false |
| 16 | 12 | The Expendables | $26,466 | -37.3% | 22 | -15 | $1,203 | $2,627,887 | 9 | Benelux Film Distributors | false | false |
| 17 | 17 | The Sorcerer's Apprentice | $25,374 | -18.1% | 27 | -3 | $939 | $2,048,239 | 10 | Walt Disney Pictures | false | false |
| 18 | 11 | Piranha 3D | $22,667 | -51.7% | 15 | -7 | $1,511 | $1,055,723 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 19 | 20 | Tamara Drewe | $21,364 | -22.3% | 12 | -1 | $1,780 | $263,910 | 5 | Cinéart | false | false |
| 20 | 19 | Step Up 3D | $20,096 | -29.9% | 15 | -12 | $1,339 | $3,515,835 | 11 | Belga Films | false | false |
| 21 | 22 | Illégal | $19,705 | -5.8% | 14 | - | $1,407 | $52,676 | 2 | N/A | false | false |
| 22 | 18 | Outside the Law | $18,714 | -36.3% | 19 | -1 | $984 | $132,318 | 3 | N/A | false | false |
| 23 | 21 | The Last Exorcism | $17,596 | -19.7% | 10 | - | $1,759 | $251,993 | 5 | Cinéart | false | false |
| 24 | 24 | Toy Story 3 | $16,126 | +20.7% | 23 | -2 | $701 | $5,452,142 | 17 | Walt Disney Pictures | false | false |
| 25 | 16 | Dinner for Schmucks | $15,395 | -53.5% | 15 | -6 | $1,026 | $223,042 | 3 | Universal Pictures International (UPI) | false | false |
| 26 | 25 | Heartbeats | $13,341 | +2.1% | 8 | -1 | $1,667 | $31,693 | 2 | ABC Distribution | false | false |
| 27 | 26 | Shrek Forever After | $12,441 | -3.7% | 18 | -8 | $691 | $4,892,039 | 14 | Universal Pictures International (UPI) | false | false |
| 28 | 28 | Twelve | $10,718 | -9.4% | 11 | - | $974 | $161,366 | 4 | Benelux Film Distributors | false | false |
| 29 | 23 | The Switch | $10,211 | -28.4% | 8 | -3 | $1,276 | $677,950 | 8 | Paradiso Entertainment | false | false |
| 30 | 27 | Salt | $8,848 | -31.3% | 2 | -8 | $4,424 | $1,752,219 | 11 | Sony Pictures Releasing | false | false |
| 31 | 30 | Special Treatment | $8,286 | -7.7% | 4 | - | $2,071 | $18,749 | 2 | Cinéart | false | false |
| 32 | 33 | The Karate Kid | $7,039 | +28.6% | 8 | -6 | $879 | $2,347,457 | 13 | Sony Pictures Releasing | false | false |
| 33 | - | A Screaming Man | $5,268 | - | 5 | - | $1,053 | $5,418 | 1 | Cinéart | true | false |
| 34 | 34 | Tinker Bell and the Lost Treasure | $5,085 | +19.7% | 7 | -1 | $726 | $165,554 | 9 | Walt Disney Pictures | false | false |
| 35 | 32 | The Last Airbender | $4,594 | -44.3% | 11 | -3 | $417 | $3,248,631 | 12 | Universal Pictures International (UPI) | false | false |
| 36 | 31 | The Tree | $3,562 | -59.2% | 9 | -1 | $395 | $235,825 | 8 | Cinéart | false | false |
| 37 | 38 | The Secret in Their Eyes | $3,074 | +23.1% | 5 | -2 | $614 | $333,661 | 19 | N/A | false | false |
| 38 | 37 | Benda Bilili! | $2,942 | -12.6% | 3 | -1 | $980 | $22,973 | 4 | Cinéart | false | false |
| 39 | 39 | Solutions locales pour un désordre global | $2,638 | +13.4% | 5 | - | $527 | $53,242 | 6 | N/A | false | false |
| 40 | 36 | Uncle Boonmee Who Can Recall His Past Lives | $2,291 | -35.1% | 6 | - | $381 | $56,740 | 7 | N/A | false | false |
| 41 | 43 | Letters to Juliet | $1,809 | +88.8% | 12 | +2 | $150 | $356,394 | 8 | Belga Films | false | false |
| 42 | 50 | The Runaways | $1,791 | +347.8% | 3 | +1 | $597 | $25,396 | 5 | Belga Films | false | false |
| 43 | 41 | The Killer Inside Me | $1,732 | +18.2% | 5 | +1 | $346 | $174,700 | 9 | Paradiso Entertainment | false | false |
| 44 | 45 | Single by Contract | $1,139 | +57.5% | 5 | +1 | $227 | $16,050 | 5 | N/A | false | false |
| 45 | 46 | Furry Vengeance | $805 | +14% | 1 | -2 | $805 | $204,858 | 13 | Belga Films | false | false |
| 46 | 47 | Love Crime | $499 | -28.8% | 6 | -2 | $83 | $168,293 | 9 | Benelux Film Distributors | false | false |
| 47 | 48 | The Ghost Writer | $488 | - | 5 | +1 | $97 | $922,719 | 30 | Benelux Film Distributors | false | false |
| 48 | 42 | Four Lovers | $251 | -81.7% | 4 | -2 | $62 | $31,988 | 4 | Benelux Film Distributors | false | false |
| 49 | 44 | The Disappearance of Alice Creed | $251 | -68.1% | 3 | -3 | $83 | $67,983 | 5 | Benelux Film Distributors | false | false |
| 50 | 51 | Women Without Men | $79 | -45.5% | 2 | +1 | $39 | $24,702 | 7 | Benelux Film Distributors | false | false |
