| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Despicable Me | $100,891 | - | 16 | - | $6,305 | $107,571 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Eat Pray Love | $34,309 | -28.3% | 7 | - | $4,901 | $120,189 | 2 | ACME | false | false |
| 3 | - | RED | $15,732 | - | 4 | - | $3,933 | $15,732 | 1 | ACME | true | false |
| 4 | - | The Town | $13,838 | - | 4 | - | $3,459 | $13,838 | 1 | - | true | false |
| 5 | 2 | Legend of the Guardians: The Owls of Ga'Hoole | $7,903 | -74.6% | 8 | - | $987 | $110,320 | 3 | - | false | false |
| 6 | 3 | Buried | $5,809 | -54.8% | 5 | - | $1,161 | $70,986 | 3 | Incognito Films | false | false |
| 7 | 5 | The Other Guys | $5,605 | -37.3% | 6 | - | $934 | $59,183 | 3 | ACME | false | false |
| 8 | 9 | Step Up 3D | $4,400 | -5.2% | 5 | - | $880 | $300,350 | 8 | ACME | false | false |
| 9 | 4 | A Turtle's Tale: Sammy's Adventures | $4,016 | -59.7% | 4 | -3 | $1,004 | $87,766 | 5 | ACME | false | false |
| 10 | 6 | Stone | $3,141 | -62.8% | 4 | -1 | $785 | $16,961 | 2 | Incognito Films | false | false |
| 11 | 12 | Inception | $2,222 | +1.3% | 6 | +1 | $370 | $355,345 | 13 | - | false | false |
| 12 | 10 | Hong Kong Confidential | $1,750 | -58.5% | 3 | -4 | $583 | $119,963 | 5 | MEED Films | false | false |
| 13 | 8 | Chatroom | $1,366 | -76.3% | 4 | +1 | $341 | $5,857 | 2 | MEED Films | false | false |
| 14 | 7 | Resident Evil: Afterlife | $1,263 | -81.2% | 2 | -6 | $631 | $188,487 | 6 | ACME | false | false |
| 15 | 11 | Going the Distance | $895 | -64.9% | 4 | -2 | $223 | $67,977 | 6 | - | false | false |
| 16 | 15 | Of Love and Other Demons | $697 | -35.5% | 2 | - | $348 | $16,184 | 4 | Incognito Films | false | false |
| 17 | 14 | Cats & Dogs: The Revenge of Kitty Galore | $508 | -59.4% | 2 | - | $254 | $227,692 | 11 | Warner Bros. | false | false |
| 18 | 18 | Toy Story 3 | $406 | -19.3% | 3 | - | $135 | $225,632 | 15 | Universal Pictures International (UPI) | false | false |
| 19 | 16 | Soul Kitchen | $261 | -50.9% | 1 | - | $261 | $8,780 | 8 | - | false | false |
| 20 | 25 | Marmaduke | $168 | +17.5% | 3 | +1 | $56 | $28,849 | 8 | Universal Pictures International (UPI) | false | false |
| 21 | 26 | The Sorcerer's Apprentice | $152 | +120.3% | 1 | - | $152 | $94,696 | 10 | Universal Pictures International (UPI) | false | false |
| 22 | 19 | Vampires Suck | $137 | -72.8% | 1 | -1 | $137 | $70,776 | 9 | Universal Pictures International (UPI) | false | false |
| 23 | 24 | The Girl with the Dragon Tattoo | $102 | -45.5% | 1 | - | $102 | $25,692 | 9 | Incognito Films | false | false |
| 24 | 22 | All That I Love | $63 | -72.6% | 1 | - | $63 | $1,868 | 4 | - | false | false |
| 25 | - | Get Him to the Greek | $23 | - | 1 | - | $23 | $48,116 | 11 | Universal Pictures International (UPI) | false | false |
| 26 | 23 | The Expendables | $20 | -89.7% | 1 | -1 | $20 | $179,503 | 10 | Incognito Films | false | false |
| 27 | 29 | Robin Hood | $8 | -33.3% | 1 | - | $8 | $210,969 | 23 | Universal Pictures International (UPI) | false | false |
