| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Eat Pray Love | $19,968 | - | 6 | - | $3,328 | $19,968 | 1 | Sony Pictures Releasing | true | false |
| 2 | 2 | Life as We Know It | $13,592 | -17.2% | 5 | - | $2,718 | $36,764 | 2 | Warner Bros. | false | false |
| 3 | - | Garfield's Pet Force | $13,347 | - | 3 | - | $4,449 | $13,347 | 1 | - | true | false |
| 4 | - | Halloween II | $13,233 | - | 4 | - | $3,308 | $13,233 | 1 | - | true | false |
| 5 | 1 | Legend of the Guardians: The Owls of Ga'Hoole | $12,746 | -52.4% | 13 | -3 | $980 | $218,069 | 5 | Warner Bros. | false | false |
| 6 | 4 | The Other Guys | $8,444 | -5.7% | 4 | - | $2,111 | $20,718 | 2 | Sony Pictures Releasing | false | false |
| 7 | 5 | Vampires Suck | $7,290 | -16% | 4 | -1 | $1,822 | $59,654 | 4 | 20th Century Fox International | false | false |
| 8 | 3 | Piranha 3D | $6,202 | -31.8% | 5 | -1 | $1,240 | $96,643 | 7 | - | false | false |
| 9 | 7 | Solomon Kane | $6,130 | -18.7% | 4 | - | $1,532 | $47,456 | 4 | - | false | false |
| 10 | 8 | The Town | $5,379 | -16% | 4 | - | $1,344 | $28,259 | 3 | Warner Bros. | false | false |
| 11 | 6 | Resident Evil: Afterlife | $3,095 | -61.9% | 5 | -4 | $619 | $390,250 | 8 | Sony Pictures Releasing | false | false |
| 12 | 10 | Paintball | $2,500 | -38% | 3 | +1 | $833 | $8,020 | 2 | N/A | false | false |
| 13 | 11 | Wall Street: Money Never Sleeps | $1,560 | -50% | 3 | -2 | $520 | $49,496 | 6 | 20th Century Fox International | false | false |
| 14 | 9 | The Twilight Saga: Eclipse | $1,296 | -72.3% | 3 | -4 | $432 | $157,648 | 6 | - | false | false |
