| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Town | $40,221 | -24.5% | 8 | - | $5,027 | $110,457 | 2 | Warner Bros. | false | false |
| 2 | - | The Social Network | $39,181 | - | 7 | - | $5,597 | $39,181 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | Despicable Me | $30,931 | -10.6% | 5 | -2 | $6,186 | $309,682 | 6 | United International Pictures | false | false |
| 4 | - | The Hole | $30,002 | - | 8 | - | $3,750 | $30,002 | 1 | Jaguar Film International Distribution | true | false |
| 5 | 3 | Eat Pray Love | $18,397 | -35.6% | 7 | - | $2,628 | $192,507 | 4 | Sony Pictures Releasing | false | false |
| 6 | 4 | Devil | $15,555 | -20.7% | 6 | - | $2,592 | $42,013 | 2 | United International Pictures | false | false |
| 7 | - | Stone | $14,011 | - | 5 | - | $2,802 | $14,011 | 1 | N/A | true | false |
| 8 | 5 | Shanghai | $9,153 | -0.4% | 6 | - | $1,525 | $21,244 | 2 | Italian International Film | false | false |
| 9 | 6 | Step Up 3D | $6,880 | -22.6% | 3 | - | $2,293 | $526,401 | 8 | Jaguar Film International Distribution | false | false |
| 10 | 8 | Wall Street: Money Never Sleeps | $5,238 | -29.5% | 3 | -2 | $1,746 | $104,381 | 6 | 20th Century Fox International | false | false |
| 11 | 7 | Resident Evil: Afterlife | $3,184 | -61.1% | 2 | -3 | $1,592 | $195,081 | 5 | Jaguar Film International Distribution | false | false |
| 12 | - | The Young Victoria | $2,898 | - | 2 | - | $1,449 | $19,762 | 3 | N/A | false | false |
| 13 | 11 | Yanoosak | $2,892 | -20.2% | 3 | - | $964 | $8,670 | 2 | Italian International Film | false | false |
| 14 | 15 | You Again | $2,221 | +78.7% | 3 | +1 | $740 | $34,474 | 6 | Walt Disney Pictures | false | false |
| 15 | 10 | Centurion | $1,668 | -68.8% | 3 | -3 | $556 | $27,091 | 3 | N/A | false | false |
| 16 | 13 | The Other Guys | $1,526 | -56.2% | 1 | -3 | $1,526 | $115,819 | 7 | Sony Pictures Releasing | false | false |
| 17 | 16 | Knight and Day 2010 Re-release | $1,508 | +23.2% | 2 | - | $754 | $273,296 | 18 | 20th Century Fox International | false | false |
| 18 | 19 | The American | $1,164 | +34.4% | 3 | - | $388 | $49,395 | 5 | Italian International Film | false | false |
| 19 | 12 | Going the Distance | $954 | -72.7% | 1 | -2 | $954 | $67,087 | 5 | Warner Bros. | false | false |
| 20 | 17 | Dinner for Schmucks | $926 | -18% | 1 | - | $926 | $110,535 | 7 | United International Pictures | false | false |
| 21 | 22 | Cats & Dogs: The Revenge of Kitty Galore | $770 | +52.8% | 1 | - | $770 | $109,120 | 8 | Warner Bros. | false | false |
| 22 | 21 | Inception | $667 | +10.1% | 1 | - | $667 | $558,065 | 14 | Warner Bros. | false | false |
| 23 | 20 | Everyday Is a Holiday | $347 | -53.7% | 1 | -1 | $347 | $9,391 | 5 | N/A | false | false |
| 24 | 25 | The Descent: Part 2 | $337 | -6.1% | 2 | +1 | $168 | $6,373 | 4 | N/A | false | false |
| 25 | 23 | Lembi 8 Giga | $228 | -52.4% | 1 | - | $228 | $214,623 | 15 | N/A | false | false |
| 26 | 26 | The Expendables | $129 | -35.8% | 1 | -1 | $129 | $182,287 | 8 | N/A | false | false |
