| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Megamind | $499,570 | - | 75 | - | $6,660 | $499,570 | 1 | United International Pictures | true | false |
| 2 | 1 | Till My Heartaches End | $270,845 | -64.9% | 75 | -1 | $3,611 | $1,181,443 | 2 | Star Cinema | false | false |
| 3 | - | Due Date | $125,804 | - | 30 | - | $4,193 | $125,804 | 1 | Warner Bros. | true | false |
| 4 | 4 | Paranormal Activity 2 | $113,651 | -35.1% | 17 | - | $6,685 | $346,099 | 2 | United International Pictures | false | false |
| 5 | - | You Again | $108,573 | - | 50 | - | $2,171 | $108,573 | 1 | Walt Disney Pictures | true | false |
| 6 | 2 | Petrang kabayo | $83,425 | -74.6% | 50 | -20 | $1,668 | $2,596,209 | 4 | N/A | false | false |
| 7 | - | The Extraordinary Adventures of Adèle Blanc-Sec | $61,174 | - | 17 | - | $3,598 | $61,174 | 1 | Pioneer Films | true | false |
| 8 | 3 | The Social Network | $60,950 | -68.3% | 26 | -4 | $2,344 | $348,827 | 2 | Sony Pictures Releasing | false | false |
| 9 | 12 | The Town | $45,718 | +117.5% | 22 | +7 | $2,078 | $361,881 | 5 | Warner Bros. | false | false |
| 10 | 5 | White House | $43,895 | -65.8% | 48 | -28 | $914 | $507,553 | 3 | N/A | false | false |
| 11 | 7 | My Soul to Take | $35,443 | -52.7% | 19 | - | $1,865 | $125,009 | 2 | Pioneer Films | false | false |
| 12 | 6 | Life as We Know It | $30,942 | -60.8% | 22 | -3 | $1,406 | $408,687 | 3 | Warner Bros. | false | false |
| 13 | 8 | Buried | $17,278 | -69.7% | 20 | - | $863 | $105,069 | 2 | Viva International Pictures | false | false |
| 14 | 9 | RED | $14,710 | -41.4% | 24 | -6 | $612 | $310,537 | 4 | Pioneer Films | false | false |
| 15 | 10 | Legend of the Guardians: The Owls of Ga'Hoole | $9,933 | -57.7% | 3 | -1 | $3,311 | $1,470,780 | 7 | Warner Bros. | false | false |
| 16 | 13 | Piranha 3D | $7,939 | -57.6% | 20 | -5 | $396 | $562,703 | 5 | Viva International Pictures | false | false |
| 17 | 17 | Wall Street: Money Never Sleeps | $2,290 | -31.1% | 1 | -4 | $2,290 | $439,243 | 6 | 20th Century Fox International | false | false |
| 18 | 11 | Eat Pray Love | $2,187 | -90.5% | 3 | -12 | $729 | $551,174 | 5 | Sony Pictures Releasing | false | false |
| 19 | 16 | The Other Guys | $1,328 | -66.6% | 1 | -2 | $1,328 | $266,705 | 4 | Sony Pictures Releasing | false | false |
| 20 | 14 | Devil | $938 | -90.3% | 1 | -5 | $938 | $290,408 | 7 | United International Pictures | false | false |
| 21 | 15 | Charlie St. Cloud | $231 | -96.2% | 2 | -3 | $115 | $176,628 | 6 | United International Pictures | false | false |
