| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Deathly Hallows: Part 1 | $2,381,547 | - | 123 | - | $19,362 | $2,381,547 | 1 | Warner Bros. | true | false |
| 2 | 2 | Unstoppable | $197,885 | -24.7% | 55 | - | $3,597 | $629,304 | 2 | 20th Century Fox International | false | false |
| 3 | 1 | Megamind | $82,156 | -78.9% | 75 | - | $1,095 | $1,241,770 | 3 | United International Pictures | false | false |
| 4 | 4 | Till My Heartaches End | $33,622 | -67.6% | 40 | -25 | $840 | $1,386,444 | 4 | Star Cinema | false | false |
| 5 | 7 | Paranormal Activity 2 | $32,936 | -29.4% | 17 | - | $1,937 | $463,441 | 4 | United International Pictures | false | false |
| 6 | 6 | Let Me In | $25,684 | -54.5% | 17 | - | $1,510 | $93,395 | 2 | Pioneer Films | false | false |
| 7 | 3 | Easy A | $18,929 | -85.1% | 50 | - | $378 | $201,708 | 2 | Sony Pictures Releasing | false | false |
| 8 | 8 | The Extraordinary Adventures of Adèle Blanc-Sec | $13,542 | -41% | 17 | +2 | $796 | $114,502 | 3 | Pioneer Films | false | false |
| 9 | 12 | Life as We Know It | $11,449 | -13.6% | 17 | -5 | $673 | $442,891 | 5 | Warner Bros. | false | false |
| 10 | 9 | The Town | $9,139 | -56.3% | 18 | -2 | $507 | $409,872 | 7 | Warner Bros. | false | false |
| 11 | 5 | Due Date | $9,064 | -88.9% | 30 | - | $302 | $284,902 | 3 | Warner Bros. | false | false |
| 12 | 11 | Petrang kabayo | $5,720 | -66.4% | 15 | -15 | $381 | $2,647,739 | 6 | N/A | false | false |
| 13 | 14 | Buried | $3,059 | -67.2% | 12 | -3 | $254 | $122,814 | 4 | Viva International Pictures | false | false |
| 14 | 17 | Eat Pray Love | $1,839 | -46.9% | 4 | +2 | $459 | $558,434 | 7 | Sony Pictures Releasing | false | false |
| 15 | 10 | The Social Network | $1,756 | -89.8% | 10 | -5 | $175 | $381,453 | 4 | Sony Pictures Releasing | false | false |
| 16 | 16 | White House | $1,634 | -65% | 12 | -8 | $136 | $527,913 | 5 | N/A | false | false |
| 17 | 15 | Legend of the Guardians: The Owls of Ga'Hoole | $1,299 | -80.2% | 2 | - | $649 | $1,483,518 | 9 | Warner Bros. | false | false |
| 18 | 13 | You Again | $403 | -96.2% | 5 | -16 | $80 | $141,433 | 3 | Walt Disney Pictures | false | false |
| 19 | 18 | Charlie St. Cloud | $208 | -92.8% | 3 | -1 | $69 | $180,765 | 8 | United International Pictures | false | false |
