| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Deathly Hallows: Part 1 | $576,564 | -53% | 119 | -53 | $4,845 | $2,223,195 | 2 | Warner Bros. | false | false |
| 2 | - | Megamind | $210,988 | - | 90 | - | $2,344 | $221,542 | 1 | United International Pictures | true | false |
| 3 | - | The Last Exorcism | $80,132 | - | 20 | - | $4,006 | $80,132 | 1 | Andes Films | true | false |
| 4 | 2 | Paranormal Activity 2 | $50,725 | -54.8% | 32 | -7 | $1,585 | $792,793 | 4 | United International Pictures | false | false |
| 5 | - | Post Mortem | $41,861 | - | 21 | - | $1,993 | $41,861 | 1 | N/A | true | false |
| 6 | - | Never Let Me Go | $26,834 | - | 9 | - | $2,981 | $26,834 | 1 | 20th Century Fox International | true | false |
| 7 | 3 | Due Date | $20,828 | -47.6% | 16 | -13 | $1,301 | $257,822 | 4 | Warner Bros. | false | false |
| 8 | 8 | Eat Pray Love | $11,085 | -42.5% | 6 | -6 | $1,847 | $411,331 | 7 | Sony Pictures Releasing | false | false |
| 9 | 6 | The Social Network | $10,977 | -48.3% | 11 | -6 | $997 | $260,599 | 5 | Sony Pictures Releasing | false | false |
| 10 | 5 | Legend of the Guardians: The Owls of Ga'Hoole | $4,055 | -85.5% | 13 | -16 | $311 | $1,246,874 | 8 | Warner Bros. | false | false |
| 11 | 10 | RED | $2,470 | -83.3% | 2 | -12 | $1,235 | $128,790 | 4 | N/A | false | false |
| 12 | 7 | Qué pena tu vida | $2,194 | -89.6% | 2 | -21 | $1,097 | $450,302 | 6 | N/A | false | false |
| 13 | 4 | Saw 3D | $2,043 | -93.1% | 3 | -17 | $681 | $673,622 | 5 | N/A | false | false |
| 14 | 12 | The Girl Who Played with Fire | $1,324 | -82.5% | 2 | -6 | $662 | $32,952 | 3 | Andes Films | false | false |
| 15 | 9 | Life as We Know It | $1,008 | -93.3% | 2 | -11 | $504 | $223,232 | 6 | Warner Bros. | false | false |
| 16 | 11 | The Town | $728 | -90.7% | 1 | -8 | $728 | $150,373 | 5 | Warner Bros. | false | false |
| 17 | 18 | Oceans | $698 | -65.8% | 1 | -1 | $698 | $43,134 | 5 | N/A | false | false |
| 18 | 17 | Nanny McPhee Returns | $530 | -76.8% | 1 | -3 | $530 | $257,244 | 11 | United International Pictures | false | false |
