| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Deathly Hallows: Part 1 | $396,663 | -62.4% | 72 | - | $5,509 | $1,700,775 | 2 | Warner Bros. | false | false |
| 2 | - | Megamind | $305,328 | - | 49 | - | $6,231 | $305,328 | - | Paramount Pictures International | - | false |
| 3 | - | Devil | $163,013 | - | 40 | - | $4,075 | $163,013 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 2 | Hachi: A Dog's Tale | $35,356 | -63.6% | 34 | +12 | $1,039 | $322,173 | 3 | N/A | false | false |
| 5 | 6 | Ex | $23,614 | -7.8% | 8 | - | $2,951 | $60,258 | 2 | N/A | false | false |
| 6 | 3 | Paranormal Activity 2 | $22,549 | -76% | 40 | - | $563 | $952,595 | 4 | Paramount Pictures International | false | false |
| 7 | 8 | Due Date | $16,671 | -26.4% | 23 | - | $724 | $223,737 | 4 | Warner Bros. | false | false |
| 8 | 5 | Life as We Know It | $11,878 | -58.4% | 26 | - | $456 | $432,126 | 5 | Warner Bros. | false | false |
| 9 | 4 | The Grudge 3 | $10,648 | -69% | 18 | - | $591 | $136,978 | 3 | N/A | false | false |
| 10 | 9 | Avatar 2010 Special Edition | $4,482 | -72.8% | 7 | - | $640 | $232,473 | 4 | 20th Century Fox International | false | false |
| 11 | 7 | Myths and Legends: The New Alliance | $3,906 | -84.3% | 22 | - | $177 | $104,907 | 3 | N/A | false | false |
| 12 | 13 | Eat Pray Love | $2,936 | -58.5% | 2 | -2 | $1,468 | $319,969 | 6 | Sony Pictures Releasing | false | false |
| 13 | 14 | The Town | $1,188 | -78.3% | 25 | - | $47 | $244,980 | 6 | Warner Bros. | false | false |
| 14 | - | Takers 2010 Re-release | $549 | - | 1 | - | $549 | $76,163 | 7 | Sony Pictures Releasing | false | false |
| 15 | 16 | Legend of the Guardians: The Owls of Ga'Hoole | $420 | -90% | 46 | - | $9 | $1,342,807 | 8 | Warner Bros. | false | false |
| 16 | - | Nanny McPhee Returns | $323 | - | 34 | - | $9 | $596,298 | 9 | Universal Pictures International (UPI) | false | false |
| 17 | 10 | Machete | $318 | -97.9% | 3 | -15 | $106 | $73,431 | 3 | Sony Pictures Releasing | false | false |
| 18 | - | Tinker Bell and the Great Fairy Rescue | $100 | - | 25 | - | $4 | $309,056 | 11 | Walt Disney Pictures | false | false |
| 19 | 19 | Piranha 3D | $80 | -92% | 17 | - | $4 | $494,194 | 5 | N/A | false | false |
