| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Tangled | $687,730 | - | 72 | - | $9,551 | $687,730 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Harry Potter and the Deathly Hallows: Part 1 | $640,894 | -31.9% | 99 | -20 | $6,473 | $2,188,616 | 2 | Warner Bros. | false | false |
| 3 | 3 | The Zero Hour | $135,465 | +15.6% | 42 | +2 | $3,225 | $2,193,127 | 8 | N/A | false | false |
| 4 | - | Wall Street: Money Never Sleeps | $97,980 | - | 42 | - | $2,332 | $97,980 | 1 | 20th Century Fox International | true | false |
| 5 | 2 | Life as We Know It | $74,838 | -47.9% | 41 | -7 | $1,825 | $715,481 | 3 | Warner Bros. | false | false |
| 6 | 5 | 9 meses | $68,826 | +12.1% | 25 | -2 | $2,753 | $301,901 | 3 | N/A | false | false |
| 7 | 4 | Paranormal Activity 2 | $54,429 | -37.3% | 24 | -8 | $2,267 | $816,848 | 4 | United International Pictures | false | false |
| 8 | - | Muerte en alto contraste | $43,794 | - | 22 | - | $1,990 | $43,794 | 1 | N/A | true | false |
| 9 | 7 | Solomon Kane | $18,307 | -60.8% | 18 | -5 | $1,017 | $246,095 | 3 | N/A | false | false |
| 10 | 6 | Saw 3D | $16,910 | -68.7% | 12 | -9 | $1,409 | $1,123,482 | 5 | Walt Disney Pictures | false | false |
| 11 | 9 | Due Date | $13,057 | -53.5% | 12 | -17 | $1,088 | $588,987 | 4 | Warner Bros. | false | false |
| 12 | 8 | Eat Pray Love | $9,988 | -78% | 6 | -18 | $1,664 | $553,047 | 5 | Sony Pictures Releasing | false | false |
| 13 | 10 | Tinker Bell and the Great Fairy Rescue | $3,534 | -77.3% | 11 | - | $321 | $330,647 | 10 | Walt Disney Pictures | false | false |
| 14 | 14 | Extremos | $3,422 | -39.9% | 4 | -3 | $855 | $45,567 | 5 | N/A | false | false |
| 15 | 13 | Furry Vengeance | $2,893 | -66.6% | 9 | -1 | $321 | $894,932 | 13 | N/A | false | false |
| 16 | 11 | Legend of the Guardians: The Owls of Ga'Hoole | $2,351 | -79.5% | 17 | -10 | $138 | $1,779,917 | 9 | Warner Bros. | false | false |
| 17 | 15 | Despicable Me | $2,264 | -47.5% | 7 | - | $323 | $2,318,457 | 16 | United International Pictures | false | false |
| 18 | 16 | Vampires Suck | $1,468 | -62.4% | 3 | -7 | $489 | $390,695 | 5 | 20th Century Fox International | false | false |
| 19 | 17 | The Sorcerer's Apprentice | $525 | -78.8% | 3 | -4 | $175 | $2,602,267 | 13 | Walt Disney Pictures | false | false |
| 20 | 18 | Cats & Dogs: The Revenge of Kitty Galore | $436 | -58.9% | 5 | - | $87 | $1,686,271 | 14 | Warner Bros. | false | false |
