| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Tangled | $718,219 | +4.4% | 78 | +6 | $9,207 | $1,946,962 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | Harry Potter and the Deathly Hallows: Part 1 | $439,273 | -31.5% | 96 | -3 | $4,575 | $3,035,418 | 3 | Warner Bros. | false | false |
| 3 | - | The Social Network | $127,456 | - | 35 | - | $3,641 | $139,470 | 1 | Sony Pictures Releasing | true | false |
| 4 | 3 | The Zero Hour | $112,547 | -16.9% | 42 | - | $2,679 | $2,414,311 | 9 | N/A | false | false |
| 5 | 6 | 9 meses | $58,255 | -15.4% | 24 | -1 | $2,427 | $405,087 | 4 | N/A | false | false |
| 6 | 5 | Life as We Know It | $55,608 | -25.7% | 36 | -5 | $1,544 | $831,714 | 4 | Warner Bros. | false | false |
| 7 | 4 | Wall Street: Money Never Sleeps | $47,142 | -51.9% | 36 | -6 | $1,309 | $213,386 | 2 | 20th Century Fox International | false | false |
| 8 | 7 | Paranormal Activity 2 | $37,224 | -31.6% | 23 | -1 | $1,618 | $891,123 | 5 | United International Pictures | false | false |
| 9 | 8 | Muerte en alto contraste | $32,648 | -25.5% | 22 | - | $1,484 | $106,649 | 2 | N/A | false | false |
| 10 | 9 | Solomon Kane | $17,210 | -6% | 19 | +1 | $905 | $286,984 | 4 | N/A | false | false |
| 11 | 10 | Saw 3D | $8,144 | -51.8% | 9 | -3 | $904 | $1,151,381 | 6 | Walt Disney Pictures | false | false |
| 12 | 11 | Due Date | $5,194 | -60.2% | 10 | -2 | $519 | $608,206 | 5 | Warner Bros. | false | false |
| 13 | 12 | Eat Pray Love | $5,043 | -49.5% | 4 | -2 | $1,260 | $563,548 | 6 | Sony Pictures Releasing | false | false |
| 14 | 13 | Tinker Bell and the Great Fairy Rescue | $2,955 | -16.4% | 10 | -1 | $295 | $335,472 | 11 | Walt Disney Pictures | false | false |
| 15 | 16 | Legend of the Guardians: The Owls of Ga'Hoole | $1,430 | -39.2% | 11 | -6 | $130 | $1,782,720 | 10 | Warner Bros. | false | false |
| 16 | 18 | Vampires Suck | $1,299 | -11.5% | 3 | - | $433 | $397,670 | 6 | 20th Century Fox International | false | false |
| 17 | 15 | Furry Vengeance | $1,143 | -60.5% | 6 | -3 | $190 | $898,253 | 14 | N/A | false | false |
| 18 | 17 | Despicable Me | $1,022 | -54.9% | 5 | -2 | $204 | $2,320,211 | 17 | United International Pictures | false | false |
| 19 | 19 | The Sorcerer's Apprentice | $519 | -1.1% | 2 | -1 | $259 | $2,603,094 | 14 | Walt Disney Pictures | false | false |
| 20 | 20 | Cats & Dogs: The Revenge of Kitty Galore | $331 | -24.1% | 4 | -1 | $82 | $1,686,812 | 15 | Warner Bros. | false | false |
