| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Little Fockers | $3,755,601 | - | 366 | - | $10,261 | $10,669,456 | 2 | Paramount Pictures International | false | false |
| 2 | - | Gulliver's Travels | $2,885,514 | - | 411 | - | $7,020 | $7,337,526 | 2 | 20th Century Fox International | false | false |
| 3 | - | The Tourist | $2,495,668 | - | 271 | - | $9,209 | $6,055,500 | 2 | Sony Pictures Releasing | false | false |
| 4 | - | The King's Speech | $2,440,235 | - | 101 | - | $24,160 | $5,715,743 | 2 | Paramount Pictures International | false | false |
| 5 | - | Tron: Legacy | $1,666,586 | - | 356 | - | $4,681 | $10,517,630 | 3 | Walt Disney Pictures | false | false |
| 6 | - | Megamind | $1,342,203 | - | 421 | - | $3,188 | $13,157,896 | 4 | Paramount Pictures International | false | false |
| 7 | - | Love & Other Drugs | $1,051,733 | - | 239 | - | $4,400 | $5,904,186 | 3 | 20th Century Fox International | false | false |
| 8 | - | Harry Potter and the Deathly Hallows: Part 1 | $818,151 | - | 280 | - | $2,921 | $40,731,871 | 7 | Warner Bros. | false | false |
| 9 | - | The Chronicles of Narnia: The Voyage of the Dawn Treader | $752,157 | - | 384 | - | $1,958 | $11,674,704 | 5 | 20th Century Fox International | false | false |
| 10 | - | Due Date | $248,075 | - | 145 | - | $1,710 | $10,390,346 | 6 | Warner Bros. | false | false |
| 11 | - | Blue Valentine | $163,171 | - | 21 | - | $7,770 | $339,445 | 1 | Palace Films | true | false |
| 12 | - | Sarah's Key | $161,271 | - | 24 | - | $6,719 | $401,731 | 2 | Madman Entertainment | false | false |
| 13 | - | The Social Network | $129,905 | - | 47 | - | $2,763 | $12,113,374 | 10 | Sony Pictures Releasing | false | false |
| 14 | - | Heartbreaker | $112,964 | - | 22 | - | $5,134 | $281,368 | 2 | Hopscotch Films | false | false |
| 15 | - | Somewhere | $111,096 | - | 22 | - | $5,049 | $310,827 | 3 | Universal Pictures International (UPI) | false | false |
| 16 | - | Inception | $45,804 | - | 5 | - | $9,160 | $36,515,403 | 24 | Warner Bros. | false | false |
| 17 | - | Fair Game | $39,556 | - | 24 | - | $1,648 | $2,419,121 | 6 | Hoyts Distribution | false | false |
| 18 | - | Tees Maar Khan | $25,596 | - | 19 | - | $1,347 | $267,680 | 2 | Mind Blowing Films | false | false |
| 19 | - | RED | $25,007 | - | 35 | - | $714 | $8,328,597 | 10 | Icon Film Distribution | false | false |
| 20 | - | Devil | $18,333 | - | 107 | - | $171 | $1,658,511 | 5 | Universal Pictures International (UPI) | false | false |
