| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Tangled | $5,777,886 | - | 462 | - | $12,506 | $6,122,246 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Little Fockers | $2,270,499 | -39.5% | 353 | -13 | $6,432 | $15,176,197 | 3 | Paramount Pictures International | false | false |
| 3 | - | Unstoppable | $2,243,264 | - | 280 | - | $8,011 | $2,245,177 | 1 | 20th Century Fox International | true | false |
| 4 | 4 | The King's Speech | $2,175,578 | -10.8% | 107 | +6 | $20,332 | $9,360,504 | 3 | Paramount Pictures International | false | false |
| 5 | - | Morning Glory | $2,046,953 | - | 244 | - | $8,389 | $2,151,347 | 1 | Paramount Pictures International | true | false |
| 6 | 2 | Gulliver's Travels | $1,947,697 | -32.5% | 403 | -8 | $4,832 | $11,462,854 | 3 | 20th Century Fox International | false | false |
| 7 | 3 | The Tourist | $1,419,559 | -43.1% | 270 | -1 | $5,257 | $8,915,509 | 3 | Sony Pictures Releasing | false | false |
| 8 | 5 | Tron: Legacy | $977,799 | -41.3% | 362 | +6 | $2,701 | $12,467,344 | 4 | Walt Disney Pictures | false | false |
| 9 | 6 | Megamind | $656,541 | -51.1% | 317 | -104 | $2,071 | $14,718,360 | 5 | Paramount Pictures International | false | false |
| 10 | 7 | Love & Other Drugs | $568,081 | -46% | 207 | -32 | $2,744 | $7,129,153 | 4 | 20th Century Fox International | false | false |
| 11 | 8 | Harry Potter and the Deathly Hallows: Part 1 | $477,865 | -41.6% | 177 | -103 | $2,699 | $40,759,316 | 8 | Warner Bros. | false | false |
| 12 | 9 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $286,754 | -61.9% | 217 | -167 | $1,321 | $12,289,657 | 6 | 20th Century Fox International | false | false |
| 13 | 11 | Blue Valentine | $161,323 | -1.1% | 23 | +2 | $7,014 | $674,907 | 2 | Palace Films | false | false |
| 14 | 12 | Sarah's Key | $154,901 | -3.9% | 27 | +3 | $5,737 | $671,925 | 3 | Madman Entertainment | false | false |
| 15 | 14 | Heartbreaker | $91,561 | -18.9% | 25 | +3 | $3,662 | $451,294 | 3 | Hopscotch Films | false | false |
| 16 | 13 | The Social Network | $77,064 | -40.7% | 40 | -7 | $1,926 | $11,953,784 | 11 | Sony Pictures Releasing | false | false |
| 17 | 15 | Somewhere | $74,802 | -32.7% | 21 | -1 | $3,562 | $457,561 | 4 | Universal Pictures International (UPI) | false | false |
| 18 | - | No One Killed Jessica | $59,492 | - | 13 | - | $4,576 | $59,492 | 1 | Mind Blowing Films | true | false |
| 19 | 10 | Due Date | $56,811 | -77.1% | 48 | -97 | $1,183 | $10,367,478 | 7 | Warner Bros. | false | false |
| 20 | - | Hubble | $17,125 | - | 22 | - | $778 | $1,300,333 | 22 | IMAX | false | false |
