| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Tangled | $616,079 | - | 88 | - | $7,000 | $616,079 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | 1 | The Tourist | $162,308 | -17.7% | 75 | - | $2,164 | $1,482,840 | 4 | Ster-Kinekor Pictures | false | false |
| 3 | - | Love & Other Drugs | $115,396 | - | 35 | - | $3,297 | $115,396 | 1 | NuMetro Distribution | true | false |
| 4 | 3 | Burlesque | $93,801 | -33.8% | 55 | - | $1,705 | $297,297 | 2 | Ster-Kinekor Pictures | false | false |
| 5 | 2 | The Next Three Days | $89,771 | -40.1% | 50 | - | $1,795 | $296,052 | 2 | NuMetro Distribution | false | false |
| 6 | 4 | Gulliver's Travels | $71,474 | -40.7% | 61 | -3 | $1,171 | $808,605 | 4 | NuMetro Distribution | false | false |
| 7 | 6 | Little Fockers | $59,125 | -18.5% | 60 | - | $985 | $1,780,014 | 6 | United International Pictures | false | false |
| 8 | 7 | Easy A | $44,619 | -27.9% | 32 | -8 | $1,394 | $263,137 | 3 | Ster-Kinekor Pictures | false | false |
| 9 | 5 | Tron: Legacy | $43,822 | -57.4% | 37 | -31 | $1,184 | $1,526,396 | 5 | Ster-Kinekor Pictures | false | false |
| 10 | - | Splice 2010 Re-release | $21,795 | - | 21 | - | $1,037 | $21,795 | 1 | United International Pictures | true | false |
| 11 | 10 | Due Date | $20,973 | -25.8% | 27 | -6 | $776 | $1,320,166 | 7 | NuMetro Distribution | false | false |
| 12 | 12 | Made in Dagenham | $20,409 | -20.9% | 34 | - | $600 | $61,240 | 2 | United International Pictures | false | false |
| 13 | 13 | The Concert | $18,793 | -17.3% | 8 | - | $2,349 | $134,071 | 4 | United International Pictures | false | false |
| 14 | 8 | Megamind | $18,535 | -58.7% | 35 | -8 | $529 | $1,876,487 | 7 | United International Pictures | false | false |
| 15 | 9 | Secretariat | $18,383 | -42.1% | 18 | -12 | $1,021 | $126,204 | 3 | Ster-Kinekor Pictures | false | false |
| 16 | 14 | Spud | $15,370 | -32% | 22 | -7 | $698 | $2,325,383 | 9 | NuMetro Distribution | false | false |
| 17 | 15 | The Town | $12,566 | -31.9% | 21 | -4 | $598 | $372,676 | 5 | NuMetro Distribution | false | false |
| 18 | 11 | Hereafter | $7,520 | -71.4% | 12 | -18 | $626 | $116,507 | 3 | NuMetro Distribution | false | false |
| 19 | 17 | The Social Network | $5,184 | -21.4% | 5 | -2 | $1,036 | $409,084 | 13 | Ster-Kinekor Pictures | false | false |
| 20 | 18 | You Will Meet a Tall Dark Stranger | $5,143 | -4.3% | 8 | +3 | $642 | $85,277 | 5 | United International Pictures | false | false |
| 21 | 19 | Faster | $3,374 | -34.5% | 6 | -6 | $562 | $499,347 | 9 | Ster-Kinekor Pictures | false | false |
| 22 | 20 | Liefling | $3,289 | -36.1% | 6 | -2 | $548 | $1,861,194 | 11 | Indigenous Film Distribution | false | false |
| 23 | 21 | The Kids Are All Right | $1,939 | -24.3% | 2 | -1 | $969 | $58,624 | 12 | United International Pictures | false | false |
| 24 | 22 | Paranormal Activity 2 | $1,007 | -59.2% | 3 | -3 | $335 | $248,232 | 8 | United International Pictures | false | false |
