| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Rango | $1,296,512 | -40.1% | 504 | -8 | $2,572 | $7,702,913 | 3 | Paramount Pictures International | false | false |
| 2 | - | Mars Needs Moms | $1,160,898 | - | 606 | - | $1,915 | $1,160,898 | 1 | Walt Disney Pictures | true | false |
| 3 | - | Unknown | $1,075,219 | - | 383 | - | $2,807 | $1,075,219 | 1 | Warner Bros. | true | false |
| 4 | - | Private Pérez | $1,009,854 | - | 275 | - | $3,672 | $1,009,854 | 1 | Videocine | true | false |
| 5 | 3 | Battle Los Angeles | $520,565 | -36.5% | 250 | - | $2,082 | $1,711,083 | 2 | Sony Pictures Releasing | false | false |
| 6 | 2 | Presumed Guilty | $439,091 | -57.5% | 301 | -6 | $1,458 | $5,878,181 | 5 | N/A | false | false |
| 7 | 4 | The Rite | $413,014 | -42.7% | 383 | -92 | $1,078 | $10,452,034 | 5 | Warner Bros. | false | false |
| 8 | 9 | No Strings Attached | $407,901 | +20.6% | 246 | +31 | $1,658 | $2,925,199 | 4 | Paramount Pictures International | false | false |
| 9 | 6 | Black Swan | $328,533 | -23.3% | 236 | -26 | $1,392 | $8,486,763 | 6 | 20th Century Fox International | false | false |
| 10 | 7 | The King's Speech | $244,714 | -33% | 178 | - | $1,374 | $2,873,101 | 5 | Videocine | false | false |
| 11 | 5 | Big Mommas: Like Father, Like Son | $226,141 | -50.5% | 250 | -111 | $904 | $3,319,740 | 4 | 20th Century Fox International | false | false |
| 12 | 10 | Just Go with It | $142,964 | -46.1% | 150 | -102 | $953 | $7,296,952 | 6 | Sony Pictures Releasing | false | false |
| 13 | 8 | I Am Number Four | $130,337 | -61.9% | 186 | -189 | $700 | $1,601,663 | 3 | Walt Disney Pictures | false | false |
| 14 | 20 | 127 Hours | $95,396 | +70.7% | 68 | +25 | $1,402 | $675,683 | 4 | 20th Century Fox International | false | false |
| 15 | - | Blue Valentine | $65,844 | - | 50 | - | $1,316 | $65,844 | 1 | Gussi Films | true | false |
| 16 | 11 | Morning Glory | $57,441 | -69.9% | 96 | -55 | $598 | $338,789 | 2 | Paramount Pictures International | false | false |
| 17 | 13 | The Fighter | $57,227 | -44.9% | 83 | -41 | $689 | $1,230,693 | 6 | Gussi Films | false | false |
| 18 | 36 | Julia's Eyes | $50,525 | +1,128.7% | 90 | +57 | $561 | $3,208,735 | 7 | Universal Pictures International (UPI) | false | false |
| 19 | 16 | Perras | $39,956 | -49.3% | 42 | -26 | $951 | $393,077 | 3 | Gussi Films | false | false |
| 20 | 18 | Stone | $39,255 | -46% | 59 | -14 | $665 | $655,036 | 8 | N/A | false | false |
| 21 | 17 | The Kids Are All Right | $37,425 | -51% | 23 | -2 | $1,627 | $161,929 | 2 | N/A | false | false |
| 22 | 19 | True Grit | $33,691 | -52.7% | 70 | -39 | $481 | $1,368,155 | 7 | Paramount Pictures International | false | false |
| 23 | 21 | Season of the Witch | $31,177 | -40.1% | 88 | -22 | $354 | $5,039,134 | 8 | Gussi Films | false | false |
| 24 | 34 | I Spit on Your Grave | $22,819 | +296.8% | 41 | +11 | $556 | $139,209 | 3 | N/A | false | false |
| 25 | 12 | Sanctum | $13,579 | -91.8% | 65 | -231 | $208 | $1,937,947 | 4 | N/A | false | false |
| 26 | - | Antichrist | $12,653 | - | 5 | - | $2,530 | $12,653 | 1 | N/A | true | false |
| 27 | 15 | Never Let Me Go | $12,579 | -84.3% | 21 | -29 | $599 | $133,763 | 2 | 20th Century Fox International | false | false |
| 28 | 14 | Yogi Bear | $12,302 | -86.7% | 89 | -152 | $138 | $10,444,959 | 7 | Warner Bros. | false | false |
| 29 | 22 | The Girl Who Played with Fire | $11,486 | -74% | 23 | -30 | $499 | $77,176 | 2 | Gussi Films | false | false |
| 30 | 23 | Hot Tub Time Machine | $6,468 | -85.1% | 20 | -64 | $323 | $156,216 | 5 | N/A | false | false |
| 31 | 27 | Serious Moonlight | $4,056 | -56.4% | 20 | -4 | $202 | $200,318 | 7 | N/A | false | false |
| 32 | 30 | The Tourist | $3,688 | -47.9% | 7 | -6 | $526 | $5,567,289 | 10 | Sony Pictures Releasing | false | false |
| 33 | 25 | Psalm 21 | $3,519 | -89% | 14 | -29 | $251 | $54,722 | 2 | N/A | false | false |
| 34 | 24 | Faster | $2,704 | -92.4% | 18 | -60 | $150 | $133,505 | 4 | Sony Pictures Releasing | false | false |
| 35 | 32 | Burlesque | $2,438 | -64.5% | 12 | -9 | $203 | $1,152,198 | 8 | Sony Pictures Releasing | false | false |
| 36 | 38 | This Is Not a Movie | $1,884 | -26.3% | 31 | +1 | $60 | $116,801 | 8 | Videocine | false | false |
| 37 | 35 | The Maid | $1,474 | -70.7% | 2 | -3 | $737 | $8,913 | 2 | N/A | false | false |
| 38 | 37 | Sin memoria | $1,027 | -73.2% | 4 | -24 | $256 | $322,748 | 6 | Videocine | false | false |
| 39 | 26 | Sunshine Barry and the Disco Worms | $888 | -90.5% | 11 | -39 | $80 | $14,176 | 2 | N/A | false | false |
| 40 | 33 | Winter's Bone | $649 | -89.7% | 4 | -15 | $162 | $92,267 | 3 | N/A | false | false |
| 41 | 40 | Uncle Boonmee Who Can Recall His Past Lives | $593 | -14.3% | 3 | - | $197 | $9,519 | 3 | N/A | false | false |
| 42 | 39 | The Green Hornet | $463 | -64.1% | 5 | -7 | $92 | $7,894,479 | 9 | Sony Pictures Releasing | false | false |
