| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: On Stranger Tides | $141,434 | -67.8% | 38 | - | $3,721 | $760,686 | 2 | Walt Disney Pictures | false | false |
| 2 | - | The Hangover Part II | $58,037 | - | 23 | - | $2,523 | $58,037 | 1 | Warner Bros. | true | false |
| 3 | 2 | Fast Five | $16,784 | -66% | 19 | - | $883 | $643,463 | 4 | United International Pictures | false | false |
| 4 | 3 | Rio | $7,814 | -65.4% | 15 | - | $520 | $697,998 | 8 | 20th Century Fox International | false | false |
| 5 | 5 | Love.net | $7,073 | -64.1% | 15 | -2 | $471 | $924,449 | 9 | Alexandra Films | false | false |
| 6 | 6 | Priest | $6,300 | -67.5% | 12 | -2 | $525 | $110,332 | 3 | Sony Pictures Releasing | false | false |
| 7 | 7 | Water for Elephants | $6,236 | -44.5% | 7 | - | $890 | $39,483 | 3 | 20th Century Fox International | false | false |
| 8 | 4 | Thor | $5,228 | -73.6% | 11 | -1 | $475 | $567,761 | 5 | United International Pictures | false | false |
| 9 | 8 | Hall Pass | $2,312 | -71.2% | 12 | +1 | $192 | $92,107 | 4 | Warner Bros. | false | false |
| 10 | 11 | A Turtle's Tale: Sammy's Adventures | $398 | -82.5% | 4 | -1 | $99 | $51,273 | 6 | A Plus Films | false | false |
| 11 | 10 | Limitless | $385 | -83.6% | 3 | -2 | $128 | $307,201 | 10 | - | false | false |
| 12 | 9 | The Lincoln Lawyer | $335 | -91.3% | 4 | -4 | $83 | $70,124 | 6 | A Plus Films | false | false |
| 13 | 12 | Just Go with It | $286 | -87.3% | 2 | -2 | $143 | $161,463 | 10 | Alexandra Films | false | false |
| 14 | 18 | Rango | $248 | +700% | 4 | +1 | $62 | $213,089 | 12 | United International Pictures | false | false |
| 15 | 15 | The Extraordinary Adventures of Adèle Blanc-Sec | $74 | -24.5% | 5 | +1 | $14 | $23,576 | 7 | A Plus Films | false | false |
| 16 | - | Megamind | $61 | - | 1 | - | $61 | $297,929 | 24 | Forum Hungary | false | false |
| 17 | 13 | Source Code | $35 | -94.1% | 2 | -1 | $17 | $106,231 | 8 | A Plus Films | false | false |
| 18 | 14 | Tilt | $33 | -88.8% | 3 | -1 | $11 | $681,419 | 16 | A Plus Films | false | false |
| 19 | 17 | Black Swan | $26 | -25.7% | 1 | - | $26 | $70,515 | 12 | A Plus Films | false | false |
| 20 | 19 | Tangled | $7 | -68.2% | 1 | - | $7 | $910,832 | 26 | Walt Disney Pictures | false | false |
