| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: On Stranger Tides | $5,569,835 | -43.8% | 1,197 | -1,000 | $4,653 | $19,155,937 | 2 | Walt Disney Pictures | false | false |
| 2 | - | The Hangover Part II | $3,306,334 | - | 579 | - | $5,710 | $3,306,334 | 1 | Warner Bros. | true | false |
| 3 | 2 | Fast Five | $1,263,885 | -43.1% | 477 | -661 | $2,649 | $24,071,567 | 4 | Universal Pictures International (UPI) | false | false |
| 4 | - | Hoodwinked Too! Hood vs. Evil | $585,946 | - | 390 | - | $1,502 | $585,946 | 1 | Gussi Films | true | false |
| 5 | 3 | Thor | $335,529 | -56.9% | 356 | -378 | $942 | $19,526,277 | 5 | Paramount Pictures International | false | false |
| 6 | 6 | Water for Elephants | $155,974 | -26.1% | 147 | -10 | $1,061 | $3,013,376 | 5 | 20th Century Fox International | false | false |
| 7 | 4 | The Lincoln Lawyer | $152,473 | -46.5% | 111 | -91 | $1,373 | $1,357,044 | 3 | N/A | false | false |
| 8 | 5 | Priest | $141,073 | -33.4% | 236 | -49 | $597 | $1,880,605 | 3 | Sony Pictures Releasing | false | false |
| 9 | 7 | Rio | $84,228 | -59.6% | 197 | -147 | $427 | $26,975,210 | 8 | 20th Century Fox International | false | false |
| 10 | 9 | Barney's Version | $59,950 | -49.1% | 61 | -19 | $982 | $251,398 | 2 | N/A | false | false |
| 11 | 11 | Red Riding Hood | $51,238 | -17.6% | 83 | -6 | $617 | $4,024,985 | 6 | Warner Bros. | false | false |
| 12 | 10 | The Mechanic | $46,933 | -32% | 49 | -28 | $957 | $947,711 | 6 | N/A | false | false |
| 13 | 8 | Limitless | $33,266 | -72.9% | 43 | -82 | $773 | $2,857,621 | 6 | Gussi Films | false | false |
| 14 | - | Bitten Bullet | $25,948 | - | 32 | - | $810 | $25,948 | 1 | N/A | true | false |
| 15 | - | Chain Letter | $24,336 | - | 49 | - | $496 | $24,336 | 1 | N/A | true | false |
| 16 | - | The Infidel | $23,714 | - | 13 | - | $1,824 | $23,827 | 1 | N/A | true | false |
| 17 | 25 | African Cats | $11,417 | +716.1% | 37 | +31 | $308 | $211,407 | 6 | Walt Disney Pictures | false | false |
| 18 | 15 | Hop | $7,282 | -66.7% | 36 | -32 | $202 | $7,420,104 | 7 | Universal Pictures International (UPI) | false | false |
| 19 | 12 | Hall Pass | $6,670 | -80.4% | 18 | -23 | $370 | $1,852,113 | 7 | Warner Bros. | false | false |
| 20 | 17 | Garfield's Pet Force | $5,675 | -55.6% | 17 | -8 | $333 | $290,562 | 4 | N/A | false | false |
| 21 | 16 | Certified Copy | $4,692 | -76.1% | 5 | -8 | $938 | $94,809 | 3 | N/A | false | false |
| 22 | - | Puzzle | $4,254 | - | 4 | - | $1,063 | $4,254 | 1 | N/A | true | false |
| 23 | 22 | Come Undone | $2,832 | +20.7% | 4 | - | $708 | $43,977 | 4 | N/A | false | false |
| 24 | 18 | Hideaway | $2,302 | -81.4% | 6 | -5 | $383 | $24,158 | 2 | N/A | false | false |
| 25 | 13 | Scream 4 | $2,069 | -93.8% | 12 | -38 | $172 | $2,378,267 | 7 | N/A | false | false |
| 26 | 19 | The Stoning of Soraya M. | $2,035 | -79.5% | 6 | -9 | $339 | $59,561 | 3 | Gussi Films | false | false |
| 27 | 27 | Faster | $943 | +5.4% | 7 | -2 | $134 | $421,869 | 14 | Sony Pictures Releasing | false | false |
| 28 | 26 | Battle Los Angeles | $533 | -47.3% | 4 | +1 | $133 | $4,230,173 | 12 | Sony Pictures Releasing | false | false |
| 29 | 28 | Winnie the Pooh | $347 | -50.3% | 2 | -2 | $173 | $335,951 | 7 | Walt Disney Pictures | false | false |
| 30 | 30 | Inside Job | $198 | -19.5% | 2 | - | $99 | $50,438 | 6 | N/A | false | false |
| 31 | 24 | Mother's Day | $64 | -96.6% | 7 | -12 | $9 | $50,581 | 3 | Videocine | false | false |
