| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: On Stranger Tides | $1,121,397 | -35.7% | 187 | -3 | $5,996 | $10,881,203 | 4 | Walt Disney Pictures | false | false |
| 2 | 2 | The Hangover Part II | $1,030,036 | -29.5% | 108 | - | $9,537 | $5,356,327 | 3 | Warner Bros. | false | false |
| 3 | 3 | X-Men: First Class | $348,158 | -42.3% | 92 | +1 | $3,784 | $1,171,846 | 2 | Warner Bros. | false | false |
| 4 | - | Source Code | $288,777 | - | 58 | - | $4,978 | $348,156 | 1 | Entertainment One | true | false |
| 5 | - | Penny's Shadow | $156,783 | - | 100 | - | $1,567 | $203,668 | 1 | Independent Films | true | false |
| 6 | 4 | Rio | $153,573 | -55% | 125 | -6 | $1,228 | $5,051,301 | 8 | Warner Bros. | false | false |
| 7 | - | Rabat | $148,385 | - | 21 | - | $7,065 | $176,239 | 1 | Benelux Film Distributors | true | false |
| 8 | 6 | Insidious | $144,060 | -19.9% | 35 | +3 | $4,116 | $438,894 | 2 | Entertainment One | false | false |
| 9 | 9 | The Tree of Life | $135,840 | +17.7% | 16 | +1 | $8,490 | $306,460 | 2 | Independent Films | false | false |
| 10 | 7 | Gooische vrouwen | $123,628 | -22.9% | 95 | -12 | $1,301 | $20,900,030 | 14 | Independent Films | false | false |
| 11 | 5 | Fast Five | $122,479 | -39.6% | 69 | -18 | $1,775 | $4,664,732 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | 8 | Something Borrowed | $105,647 | -15.1% | 68 | -1 | $1,553 | $378,185 | 2 | Paradiso Entertainment | false | false |
| 13 | 10 | Unknown | $40,494 | -35.8% | 21 | -18 | $1,928 | $1,006,349 | 5 | Warner Bros. | false | false |
| 14 | 12 | Tous les soleils | $39,979 | +35.1% | 17 | - | $2,351 | $96,340 | 2 | Benelux Film Distributors | false | false |
| 15 | 16 | Black Butterflies | $27,507 | +17.6% | 36 | - | $764 | $1,164,358 | 11 | A-Film Distribution | false | false |
| 16 | 14 | Nothing to Declare | $26,139 | +9.8% | 22 | - | $1,188 | $128,179 | 3 | Paradiso Entertainment | false | false |
| 17 | - | Loose Cannons | $18,472 | - | 9 | - | $2,052 | $118,544 | 4 | Cinemien | false | false |
| 18 | 20 | The King's Speech | $17,839 | +14.3% | 22 | - | $810 | $5,218,784 | 17 | Paradiso Entertainment | false | false |
| 19 | 13 | Winnie the Pooh | $16,010 | -44.3% | 67 | -30 | $238 | $480,127 | 8 | Walt Disney Pictures | false | false |
| 20 | 11 | Conference of Animals | $12,736 | -72.9% | 29 | -10 | $439 | $431,847 | 7 | Entertainment One | false | false |
