| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cars 2 | $128,366 | - | 21 | - | $6,112 | $128,366 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Kung Fu Panda 2 | $80,970 | -32.1% | 17 | -3 | $4,762 | $524,301 | 3 | Paramount Pictures International | false | false |
| 3 | - | The Roommate | $18,998 | - | 5 | - | $3,799 | $18,998 | 1 | Sony Pictures Releasing | true | false |
| 4 | 4 | The Hangover Part II | $18,277 | -6.6% | 8 | - | $2,284 | $192,123 | 5 | Warner Bros. | false | false |
| 5 | 3 | X-Men: First Class | $16,127 | -34.5% | 10 | -5 | $1,612 | $206,155 | 4 | 20th Century Fox International | false | false |
| 6 | 2 | Pirates of the Caribbean: On Stranger Tides | $11,597 | -56.5% | 10 | -8 | $1,159 | $752,938 | 6 | Walt Disney Pictures | false | false |
| 7 | 5 | Skyline | $8,864 | -11.5% | 3 | - | $2,954 | $24,653 | 2 | - | false | false |
| 8 | 8 | Sanctum | $5,215 | -12.3% | 4 | +1 | $1,303 | $19,569 | 2 | N/A | false | false |
| 9 | 7 | Biutiful | $3,985 | -34.8% | 5 | -1 | $797 | $14,304 | 2 | - | false | false |
| 10 | 6 | Let Me In | $3,560 | -62.3% | 4 | - | $890 | $23,361 | 2 | United International Pictures | false | false |
| 11 | 9 | Fast Five | $2,282 | -59.2% | 2 | -2 | $1,141 | $273,801 | 8 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | African Cats | $738 | -78.2% | 2 | -5 | $369 | $15,837 | 3 | Walt Disney Pictures | false | false |
