| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Jock the Hero Dog | $374,681 | - | 84 | - | $4,460 | $374,681 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | 1 | Harry Potter and the Deathly Hallows: Part 2 | $262,357 | -39.1% | 93 | -10 | $2,821 | $2,336,267 | 3 | NuMetro Distribution | false | false |
| 3 | 3 | Horrible Bosses | $163,643 | -15.5% | 51 | - | $3,208 | $458,761 | 2 | NuMetro Distribution | false | false |
| 4 | - | Super 8 | $153,817 | - | 58 | - | $2,652 | $153,817 | 1 | United International Pictures | true | false |
| 5 | 2 | Cars 2 | $137,872 | -37.5% | 71 | -15 | $1,941 | $2,361,099 | 4 | Ster-Kinekor Pictures | false | false |
| 6 | 4 | Transformers: Dark of the Moon | $117,994 | -37.9% | 55 | -9 | $2,145 | $3,454,148 | 5 | United International Pictures | false | false |
| 7 | - | Larry Crowne | $98,962 | - | 42 | - | $2,356 | $98,962 | 1 | NuMetro Distribution | true | false |
| 8 | 5 | Honey 2 | $94,815 | -4.2% | 35 | - | $2,709 | $225,895 | 2 | United International Pictures | false | false |
| 9 | 7 | Madea's Big Happy Family | $46,875 | -19.9% | 29 | -6 | $1,616 | $744,186 | 5 | Ster-Kinekor Pictures | false | false |
| 10 | 6 | Something Borrowed | $42,543 | -38% | 41 | -7 | $1,037 | $620,346 | 4 | NuMetro Distribution | false | false |
| 11 | 9 | The Bang Bang Club | $30,470 | -37.7% | 51 | -2 | $597 | $113,868 | 2 | Indigenous Film Distribution | false | false |
| 12 | 8 | Bridesmaids | $25,490 | -48.1% | 25 | -10 | $1,019 | $987,402 | 6 | United International Pictures | false | false |
| 13 | 12 | Insidious | $23,512 | -8% | 15 | - | $1,567 | $60,559 | 2 | NuMetro Distribution | false | false |
| 14 | 11 | The Hangover Part II | $14,568 | -56% | 26 | -13 | $560 | $2,733,235 | 10 | NuMetro Distribution | false | false |
| 15 | 10 | Kung Fu Panda 2 | $9,270 | -72.2% | 14 | -20 | $662 | $3,130,421 | 8 | United International Pictures | false | false |
| 16 | 16 | Jumping the Broom | $9,119 | -11.5% | 10 | -2 | $911 | $371,520 | 7 | Ster-Kinekor Pictures | false | false |
| 17 | 17 | Biutiful | $7,793 | -21.5% | 3 | - | $2,597 | $23,222 | 2 | Ster-Kinekor Pictures | false | false |
| 18 | 19 | Chalet Girl | $7,023 | -11.8% | 10 | - | $702 | $19,284 | 2 | United International Pictures | false | false |
| 19 | 18 | The Lincoln Lawyer | $6,082 | -28.9% | 11 | +2 | $552 | $468,626 | 9 | NuMetro Distribution | false | false |
| 20 | - | The Beaver | $6,024 | - | 10 | - | $602 | $6,024 | 1 | NuMetro Distribution | true | false |
| 21 | 20 | All Good Things 2010 Re-release | $5,113 | -28.8% | 6 | - | $852 | $166,782 | 6 | Ster-Kinekor Pictures | false | false |
| 22 | 14 | Scream 4 | $4,140 | -70.8% | 9 | -14 | $460 | $347,353 | 4 | Ster-Kinekor Pictures | false | false |
| 23 | 23 | The Adjustment Bureau | $3,436 | +9.4% | 6 | -2 | $572 | $369,078 | 8 | United International Pictures | false | false |
| 24 | 15 | Pirates of the Caribbean: On Stranger Tides | $3,284 | -73.7% | 3 | -9 | $1,094 | $3,651,559 | 11 | Ster-Kinekor Pictures | false | false |
| 25 | 25 | My Hunter's Heart | $522 | +39.9% | 2 | +1 | $261 | $5,015 | 4 | United International Pictures | false | false |
