| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Smurfs | $958,107 | - | 56 | - | $17,109 | $958,107 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Captain America: The First Avenger | $251,527 | - | 33 | - | $7,622 | $251,527 | 1 | United International Pictures | true | false |
| 3 | 1 | Harry Potter and the Deathly Hallows: Part 2 | $152,069 | -49.7% | 44 | -3 | $3,456 | $3,023,805 | 4 | Warner Bros. | false | false |
| 4 | 2 | Horrible Bosses | $148,363 | -19.2% | 25 | -1 | $5,934 | $726,381 | 3 | Warner Bros. | false | false |
| 5 | 5 | Bridesmaids | $113,037 | -12.3% | 20 | -2 | $5,651 | $1,100,878 | 5 | United International Pictures | false | false |
| 6 | - | Green Lantern | $93,990 | - | 28 | - | $3,356 | $105,849 | 1 | Warner Bros. | true | false |
| 7 | 3 | Super 8 | $79,473 | -48.1% | 25 | -6 | $3,178 | $305,489 | 2 | United International Pictures | false | false |
| 8 | 4 | Kung Fu Panda 2 | $67,794 | -47.7% | 36 | -5 | $1,883 | $2,708,419 | 8 | United International Pictures | false | false |
| 9 | 6 | Zookeeper | $65,400 | -42.5% | 20 | - | $3,270 | $532,846 | 3 | Sony Pictures Releasing | false | false |
| 10 | 8 | Winnie the Pooh | $42,920 | -36.2% | 25 | +1 | $1,716 | $262,913 | 3 | Walt Disney Pictures | false | false |
| 11 | 7 | Cars 2 | $39,236 | -51.9% | 30 | -8 | $1,307 | $1,362,498 | 7 | Walt Disney Pictures | false | false |
| 12 | 9 | Transformers: Dark of the Moon | $29,735 | -50.8% | 11 | -6 | $2,703 | $1,468,673 | 6 | United International Pictures | false | false |
| 13 | 11 | The Hangover Part II | $29,340 | -5.4% | 11 | -2 | $2,667 | $3,087,326 | 11 | Warner Bros. | false | false |
| 14 | 10 | Mr. Popper's Penguins | $25,506 | -42.2% | 11 | -1 | $2,318 | $488,437 | 5 | 20th Century Fox International | false | false |
| 15 | 12 | Pirates of the Caribbean: On Stranger Tides | $12,666 | -54.7% | 6 | -2 | $2,111 | $3,093,916 | 12 | Walt Disney Pictures | false | false |
