| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $652,262 | -24.2% | 61 | -4 | $10,692 | $3,747,395 | 3 | Sony Pictures Releasing | false | false |
| 2 | 2 | Rise of the Planet of the Apes | $235,427 | -10.4% | 22 | +1 | $10,701 | $744,360 | 2 | 20th Century Fox International | false | false |
| 3 | 4 | Horrible Bosses | $82,932 | -33.3% | 24 | -1 | $3,455 | $1,052,626 | 5 | Warner Bros. | false | false |
| 4 | - | Cowboys & Aliens | $70,616 | - | 26 | - | $2,716 | $70,616 | 1 | United International Pictures | true | false |
| 5 | 3 | Captain America: The First Avenger | $69,749 | -52.1% | 27 | -6 | $2,583 | $626,022 | 3 | United International Pictures | false | false |
| 6 | 6 | Bridesmaids | $63,008 | -33.7% | 16 | -4 | $3,938 | $1,360,452 | 7 | United International Pictures | false | false |
| 7 | 5 | Harry Potter and the Deathly Hallows: Part 2 | $58,846 | -47% | 24 | -9 | $2,451 | $3,329,847 | 6 | Warner Bros. | false | false |
| 8 | 7 | Kung Fu Panda 2 | $43,666 | -14.3% | 29 | -2 | $1,505 | $2,904,770 | 10 | United International Pictures | false | false |
| 9 | 8 | Winnie the Pooh | $43,397 | -8.2% | 23 | -1 | $1,886 | $434,064 | 5 | Walt Disney Pictures | false | false |
| 10 | - | Fright Night | $34,271 | - | 15 | - | $2,284 | $34,271 | 1 | Walt Disney Pictures | true | false |
| 11 | 11 | Zookeeper | $29,267 | -28.6% | 15 | -3 | $1,951 | $688,316 | 5 | Sony Pictures Releasing | false | false |
| 12 | 12 | Cars 2 | $28,133 | -5.4% | 18 | +1 | $1,562 | $1,476,698 | 9 | Walt Disney Pictures | false | false |
| 13 | 9 | Super 8 | $23,565 | -49.5% | 13 | -7 | $1,812 | $431,919 | 4 | United International Pictures | false | false |
| 14 | 13 | The Hangover Part II | $15,116 | -35.8% | 8 | -3 | $1,889 | $3,145,878 | 13 | Warner Bros. | false | false |
| 15 | 14 | Mr. Popper's Penguins | $13,944 | -36.3% | 6 | -5 | $2,324 | $562,350 | 7 | 20th Century Fox International | false | false |
| 16 | 10 | Green Lantern | $13,554 | -68.6% | 13 | -15 | $1,042 | $221,078 | 3 | Warner Bros. | false | false |
