| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Rise of the Planet of the Apes | $3,686,179 | -15.5% | 628 | -74 | $5,869 | $21,815,494 | 3 | 20th Century Fox International | false | false |
| 2 | - | Cowboys & Aliens | $3,445,317 | - | 480 | - | $7,177 | $3,445,317 | 1 | Paramount Pictures International | true | false |
| 3 | 3 | The Smurfs | $2,987,826 | +23.8% | 539 | +24 | $5,543 | $20,075,822 | 4 | Sony Pictures Releasing | false | false |
| 4 | 2 | Captain America: The First Avenger | $2,217,153 | -33.6% | 500 | - | $4,434 | $6,650,841 | 2 | Paramount Pictures International | false | false |
| 5 | - | You Will Be My Son | $1,917,300 | - | 302 | - | $6,348 | $1,917,300 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 4 | Horrible Bosses | $1,475,331 | -23.8% | 253 | -5 | $5,831 | $3,746,033 | 2 | Warner Bros. | false | false |
| 7 | 6 | Cars 2 | $1,408,660 | -0.2% | 662 | -18 | $2,127 | $25,613,486 | 5 | Walt Disney Pictures | false | false |
| 8 | 5 | The Skin I Live In | $1,193,650 | -17.6% | 350 | +69 | $3,410 | $3,141,673 | 2 | N/A | false | false |
| 9 | 9 | Super 8 | $946,368 | -21.9% | 450 | -72 | $2,103 | $12,234,142 | 4 | Paramount Pictures International | false | false |
| 10 | - | One Day | $931,243 | - | 197 | - | $4,727 | $931,243 | 1 | N/A | true | false |
| 11 | 7 | Green Lantern | $846,379 | -35.3% | 400 | -35 | $2,115 | $6,862,072 | 3 | Warner Bros. | false | false |
| 12 | 10 | Harry Potter and the Deathly Hallows: Part 2 | $842,199 | -27% | 414 | -199 | $2,034 | $65,096,784 | 7 | Warner Bros. | false | false |
| 13 | - | Beloved | $803,689 | - | 232 | - | $3,464 | $803,689 | 1 | N/A | true | false |
| 14 | 11 | Bridesmaids | $646,532 | -28.4% | 216 | -59 | $2,993 | $3,963,693 | 3 | Universal Pictures International (UPI) | false | false |
| 15 | 8 | Conan the Barbarian | $560,525 | -55.9% | 415 | - | $1,350 | $2,190,530 | 2 | Metropolitan Filmexport | false | false |
| 16 | - | This Must Be the Place | $515,236 | - | 151 | - | $3,412 | $515,236 | 1 | N/A | true | false |
| 17 | 13 | Melancholia | $435,996 | -18.2% | 188 | -6 | $2,319 | $2,257,374 | 3 | N/A | false | false |
| 18 | 12 | Unforgivable | $349,400 | -39.1% | 132 | +27 | $2,646 | $1,099,385 | 2 | UGC Distribution | false | false |
| 19 | 15 | Zookeeper | $302,948 | -36.6% | 174 | -57 | $1,741 | $980,101 | 2 | Sony Pictures Releasing | false | false |
| 20 | 14 | Bad Teacher | $238,193 | -54% | 151 | -98 | $1,577 | $8,755,373 | 5 | Sony Pictures Releasing | false | false |
| 21 | - | One Piece: Strong World | $76,212 | - | 20 | - | $3,810 | $76,212 | 1 | N/A | true | false |
| 22 | - | Monte Carlo | $13,727 | - | 10 | - | $1,372 | $13,727 | 1 | 20th Century Fox International | true | false |
