| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Smurfs | $693,203 | +16% | 172 | -6 | $4,030 | $7,050,309 | 4 | Sony Pictures Releasing | false | false |
| 2 | 1 | Rise of the Planet of the Apes | $585,742 | -29.2% | 105 | +1 | $5,578 | $1,826,265 | 2 | Warner Bros. | false | false |
| 3 | - | Final Destination 5 | $583,899 | - | 68 | - | $8,586 | $583,899 | 1 | Warner Bros. | true | false |
| 4 | 3 | Harry Potter and the Deathly Hallows: Part 2 | $429,649 | -15.4% | 169 | -12 | $2,542 | $17,618,491 | 7 | Warner Bros. | false | false |
| 5 | - | Cowboys & Aliens | $367,778 | - | 78 | - | $4,715 | $442,883 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 5 | Horrible Bosses | $226,457 | +3.2% | 82 | -4 | $2,761 | $2,480,637 | 5 | Warner Bros. | false | false |
| 7 | 6 | Mr. Popper's Penguins | $219,596 | +3.3% | 99 | +4 | $2,218 | $1,270,261 | 3 | Warner Bros. | false | false |
| 8 | 4 | Super 8 | $173,394 | -28.5% | 87 | +3 | $1,993 | $1,427,609 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | Cars 2 | $127,865 | +19.2% | 150 | -10 | $852 | $6,214,197 | 8 | Walt Disney Pictures | false | false |
| 10 | - | Melancholia | $127,471 | - | 21 | - | $6,070 | $137,560 | 1 | Wild Bunch Distribution | true | false |
| 11 | 10 | Monte Carlo | $78,808 | -1.6% | 49 | +1 | $1,608 | $1,065,691 | 5 | Warner Bros. | false | false |
| 12 | 9 | Honey 2 | $73,156 | -10.9% | 30 | +1 | $2,438 | $737,970 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | Bridesmaids | $58,025 | -18.5% | 45 | -8 | $1,289 | $2,626,010 | 8 | Universal Pictures International (UPI) | false | false |
| 14 | 13 | A Separation | $46,055 | +4% | 13 | - | $3,542 | $231,825 | 3 | Cinéart | false | false |
| 15 | 8 | Captain America: The First Avenger | $45,138 | -46.2% | 27 | -36 | $1,671 | $1,632,726 | 5 | Universal Pictures International (UPI) | false | false |
| 16 | 15 | Kung Fu Panda 2 | $41,749 | +26.5% | 73 | -14 | $571 | $5,457,209 | 11 | Universal Pictures International (UPI) | false | false |
| 17 | 14 | Larry Crowne | $41,670 | -3% | 33 | -8 | $1,262 | $428,946 | 4 | Entertainment One | false | false |
| 18 | 17 | Pina | $30,522 | +13.2% | 16 | +1 | $1,907 | $717,245 | 8 | Cinéart | false | false |
| 19 | - | The First Beautiful Thing 2011 Re-release | $28,585 | - | 14 | - | $2,041 | $36,643 | 1 | Cinéart | true | false |
| 20 | - | Hanni & Nanni 2011 Re-release | $27,097 | - | 31 | - | $874 | $31,600 | 1 | Moonlight Films | true | false |
