| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Horrible Bosses | $2,314,984 | -31% | 342 | +3 | $6,768 | $6,976,679 | 2 | Warner Bros. | false | false |
| 2 | 2 | Red Dog | $1,766,467 | -13.9% | 260 | +3 | $6,794 | $13,777,929 | 5 | Roadshow Films | false | false |
| 3 | - | The Help | $1,113,903 | - | 280 | - | $3,978 | $1,720,596 | 1 | Walt Disney Pictures | true | false |
| 4 | - | Final Destination 5 | $1,028,163 | - | 158 | - | $6,507 | $1,028,163 | 1 | Warner Bros. | true | false |
| 5 | 3 | Friends with Benefits | $796,532 | -46% | 247 | -4 | $3,224 | $6,557,469 | 3 | Sony Pictures Releasing | false | false |
| 6 | 4 | Cowboys & Aliens | $693,839 | -35.9% | 243 | +8 | $2,855 | $4,990,009 | 3 | Paramount Pictures International | false | false |
| 7 | 5 | Rise of the Planet of the Apes | $623,279 | -32.4% | 188 | -50 | $3,315 | $14,720,515 | 5 | 20th Century Fox International | false | false |
| 8 | - | One Day | $605,862 | - | 163 | - | $3,716 | $605,862 | 1 | Universal Pictures International (UPI) | true | false |
| 9 | 11 | The Guard | $314,499 | +0.2% | 48 | -1 | $6,552 | $813,698 | 2 | Paramount Pictures International | false | false |
| 10 | 7 | Harry Potter and the Deathly Hallows: Part 2 | $296,961 | -36.9% | 132 | -47 | $2,249 | $55,239,019 | 8 | Warner Bros. | false | false |
| 11 | 6 | Green Lantern | $274,714 | -53.3% | 180 | -181 | $1,526 | $6,965,641 | 4 | Warner Bros. | false | false |
| 12 | - | Bodyguard | $230,916 | - | 16 | - | $14,432 | $266,151 | 1 | Mind Blowing Films | true | false |
| 13 | 8 | Jane Eyre | $178,233 | -50.8% | 102 | -48 | $1,747 | $3,027,143 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | 9 | Priest | $153,882 | -53.4% | 104 | - | $1,479 | $615,837 | 2 | Sony Pictures Releasing | false | false |
| 15 | 12 | Beginners | $122,020 | -19% | 25 | - | $4,880 | $410,569 | 2 | Hopscotch Films | false | false |
| 16 | 13 | Senna | $116,267 | -15.9% | 43 | -4 | $2,703 | $1,238,002 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | 10 | Conan the Barbarian | $90,558 | -72% | 60 | -153 | $1,509 | $1,484,160 | 3 | Roadshow Films | false | false |
| 18 | - | Chalet Girl | $77,342 | - | 104 | - | $743 | $77,342 | 1 | Paramount Pictures International | true | false |
| 19 | 15 | Captain America: The First Avenger | $43,976 | -59% | 30 | -74 | $1,465 | $11,108,979 | 6 | Paramount Pictures International | false | false |
| 20 | 17 | Pina | $40,018 | -19.1% | 10 | - | $4,001 | $203,612 | 3 | Hopscotch Films | false | false |
