| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Conan the Barbarian | $46,618 | -26.4% | 18 | -3 | $2,589 | $161,720 | 2 | N/A | false | false |
| 2 | 1 | The Smurfs | $46,294 | -27.9% | 22 | - | $2,104 | $398,125 | 3 | Sony Pictures Releasing | false | false |
| 3 | - | Green Lantern | $32,186 | - | 16 | - | $2,011 | $32,186 | 1 | Warner Bros. | true | false |
| 4 | 3 | Horrible Bosses | $23,642 | +30% | 13 | -1 | $1,818 | $155,786 | 3 | Warner Bros. | false | false |
| 5 | - | Shark Night | $22,618 | - | 10 | - | $2,261 | $22,618 | 1 | Forum Hungary | true | false |
| 6 | - | Colombiana | $19,853 | - | 15 | - | $1,323 | $19,853 | 1 | N/A | true | false |
| 7 | 4 | The Change-Up | $15,736 | +34.3% | 10 | -1 | $1,573 | $50,065 | 2 | United International Pictures | false | false |
| 8 | 5 | Cowboys & Aliens | $8,002 | -5.4% | 14 | -3 | $571 | $144,101 | 4 | United International Pictures | false | false |
| 9 | 6 | Rise of the Planet of the Apes | $7,631 | -0.9% | 14 | -1 | $545 | $177,883 | 5 | 20th Century Fox International | false | false |
| 10 | 8 | Harry Potter and the Deathly Hallows: Part 2 | $7,052 | +12.2% | 9 | -2 | $783 | $574,161 | 8 | Warner Bros. | false | false |
| 11 | 12 | Cars 2 | $3,891 | +49% | 8 | -3 | $486 | $501,142 | 11 | Walt Disney Pictures | false | false |
| 12 | 11 | Winnie the Pooh | $3,704 | +28.4% | 12 | - | $308 | $146,552 | 7 | Walt Disney Pictures | false | false |
| 13 | 7 | Friends with Benefits | $3,468 | -46.8% | 11 | -1 | $315 | $199,379 | 6 | Sony Pictures Releasing | false | false |
| 14 | 9 | Fright Night | $2,932 | -49.1% | 7 | -9 | $418 | $44,170 | 3 | Walt Disney Pictures | false | false |
| 15 | 13 | Transformers: Dark of the Moon | $2,161 | +11.4% | 5 | -5 | $432 | $791,697 | 10 | United International Pictures | false | false |
| 16 | 10 | Captain America: The First Avenger | $1,684 | -44.8% | 3 | -4 | $561 | $241,576 | 6 | United International Pictures | false | false |
| 17 | 15 | Pirates of the Caribbean: On Stranger Tides | $1,327 | +42.7% | 6 | - | $221 | $1,505,391 | 16 | Walt Disney Pictures | false | false |
| 18 | 16 | Fast Five | $1,017 | +37.1% | 5 | -1 | $203 | $787,345 | 18 | United International Pictures | false | false |
| 19 | 18 | Kung Fu Panda 2 | $940 | +74.7% | 4 | - | $235 | $531,911 | 14 | United International Pictures | false | false |
| 20 | 17 | The Hangover Part II | $327 | -52.1% | 3 | -3 | $109 | $516,506 | 15 | Warner Bros. | false | false |
| 21 | 20 | The Tree of Life | $171 | -10% | 2 | +1 | $85 | $91,977 | 14 | N/A | false | false |
| 22 | 25 | Mr. Popper's Penguins | $155 | +68.5% | 3 | -2 | $51 | $114,544 | 10 | 20th Century Fox International | false | false |
| 23 | 27 | Tangled | $98 | +1,300% | 2 | +1 | $49 | $909,890 | 40 | Walt Disney Pictures | false | false |
| 24 | 21 | Love.net | $61 | -67.6% | 2 | -1 | $30 | $999,188 | 23 | Alexandra Films | false | false |
| 25 | 23 | Larry Crowne | $42 | -65.6% | 3 | -1 | $14 | $69,995 | 9 | N/A | false | false |
| 26 | 14 | What War May Bring | $33 | -97.5% | 1 | - | $33 | $7,719 | 7 | N/A | false | false |
