| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Smurfs | $48,144 | +6.1% | 18 | -4 | $2,674 | $547,714 | 5 | Sony Pictures Releasing | false | false |
| 2 | 1 | Cars 2 | $38,998 | -60.4% | 24 | - | $1,624 | $159,809 | 2 | Walt Disney Pictures | false | false |
| 3 | - | The Change-Up | $25,763 | - | 11 | - | $2,342 | $25,763 | 1 | United International Pictures | true | false |
| 4 | 3 | Conan the Barbarian | $25,482 | -42.7% | 13 | - | $1,960 | $93,529 | 2 | N/A | false | false |
| 5 | 4 | Horrible Bosses | $25,318 | -19.1% | 12 | - | $2,109 | $136,482 | 3 | Warner Bros. | false | false |
| 6 | - | Final Destination 5 | $16,618 | - | 12 | - | $1,384 | $16,618 | 1 | Warner Bros. | true | false |
| 7 | 5 | Bad Teacher | $15,680 | -25.4% | 11 | - | $1,425 | $52,300 | 2 | Sony Pictures Releasing | false | false |
| 8 | 6 | Harry Potter and the Deathly Hallows: Part 2 | $10,558 | -19% | 10 | -1 | $1,055 | $825,532 | 8 | Warner Bros. | false | false |
| 9 | - | The Tree of Life | $8,041 | - | 2 | - | $4,020 | $8,041 | 1 | N/A | true | false |
| 10 | 7 | Rise of the Planet of the Apes | $7,465 | -33.3% | 11 | -1 | $678 | $148,431 | 5 | 20th Century Fox International | false | false |
| 11 | 9 | Scream 4 | $7,203 | -16.5% | 8 | - | $900 | $39,824 | 3 | N/A | false | false |
| 12 | 8 | Cowboys & Aliens | $6,837 | -36.8% | 12 | -1 | $569 | $54,146 | 3 | United International Pictures | false | false |
| 13 | 10 | Green Lantern | $5,404 | -24.7% | 8 | -4 | $675 | $79,208 | 4 | Warner Bros. | false | false |
| 14 | 11 | Monte Carlo | $3,438 | -27.8% | 5 | - | $687 | $44,604 | 4 | 20th Century Fox International | false | false |
| 15 | 14 | Ironclad | $1,695 | -25.4% | 4 | -3 | $423 | $22,019 | 4 | N/A | false | false |
| 16 | 12 | Kung Fu Panda 2 | $1,378 | -62.7% | 4 | -7 | $344 | $555,726 | 14 | United International Pictures | false | false |
| 17 | 13 | Captain America: The First Avenger | $1,148 | -61% | 5 | -2 | $229 | $131,785 | 6 | United International Pictures | false | false |
