| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Smurfs | $159,495 | -23.6% | 12 | -1 | $13,291 | $501,009 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Rise of the Planet of the Apes | $66,460 | - | 9 | - | $7,384 | $66,460 | 1 | 20th Century Fox International | true | false |
| 3 | - | Final Destination 5 | $43,138 | - | 10 | - | $4,313 | $237,479 | 2 | Warner Bros. | false | false |
| 4 | - | Conan the Barbarian | $28,476 | - | 8 | - | $3,559 | $159,817 | 2 | N/A | false | false |
| 5 | - | Colombiana | $22,984 | - | 8 | - | $2,873 | $22,984 | 1 | N/A | true | false |
| 6 | - | Captain America: The First Avenger | $19,319 | - | 10 | - | $1,931 | $156,459 | 2 | United International Pictures | false | false |
| 7 | - | Crazy, Stupid, Love. | $17,379 | - | 4 | - | $4,344 | $330,534 | 7 | Warner Bros. | false | false |
| 8 | - | Tek Tek Boom | $7,951 | - | 8 | - | $993 | $58,444 | 2 | N/A | false | false |
| 9 | - | Inhale | $2,481 | - | 1 | - | $2,481 | $23,642 | 3 | Prime Pictures | false | false |
| 10 | - | Eza3et Hob | $2,312 | - | 4 | - | $578 | $13,529 | 2 | Prime Pictures | false | false |
| 11 | - | Horrible Bosses | $1,702 | - | 1 | - | $1,702 | $319,676 | 10 | Warner Bros. | false | false |
| 12 | - | 22 Bullets | $1,275 | - | 2 | - | $637 | $35,692 | 3 | N/A | false | false |
| 13 | - | Prom | $1,180 | - | 2 | - | $590 | $26,074 | 3 | Walt Disney Pictures | false | false |
| 14 | - | From Prada to Nada | $815 | - | 1 | - | $815 | $13,402 | 3 | N/A | false | false |
| 15 | - | A Good Night | $778 | - | 1 | - | $778 | $22,707 | 2 | N/A | false | false |
| 16 | - | Mr. Popper's Penguins | $764 | - | 1 | - | $764 | $268,932 | 10 | 20th Century Fox International | false | false |
| 17 | - | Cars 2 | $435 | - | 2 | - | $217 | $214,988 | 12 | Walt Disney Pictures | false | false |
| 18 | - | Vincere | $346 | - | 1 | - | $346 | $3,480 | 4 | Italian International Film | false | false |
| 19 | - | Creation | $326 | - | 1 | - | $326 | $2,018 | 4 | N/A | false | false |
| 20 | - | The Last Station 2010 Re-release | $246 | - | 1 | - | $246 | $2,982 | 4 | N/A | false | false |
| 21 | - | The True Story of Puss'N Boots | $160 | - | 1 | - | $160 | $22,393 | 7 | N/A | false | false |
| 22 | - | London Boulevard | $120 | - | 1 | - | $120 | $32,812 | 6 | N/A | false | false |
| 23 | - | The Conspirator | $113 | - | 1 | - | $113 | $18,243 | 4 | Italian International Film | false | false |
