| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $19,357 | +31.8% | 11 | - | $1,759 | $517,969 | 9 | Sony Pictures Releasing | false | false |
| 2 | 2 | Friends with Benefits | $11,969 | +1.5% | 7 | - | $1,709 | $30,775 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | What's Your Number? | $11,203 | - | 7 | - | $1,600 | $19,828 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | Johnny English Reborn | $10,289 | +8.7% | 8 | - | $1,286 | $87,282 | 4 | United International Pictures | false | false |
| 5 | 4 | Crazy, Stupid, Love. | $7,397 | +18% | 7 | - | $1,056 | $40,100 | 3 | Warner Bros. | false | false |
| 6 | 6 | Cars 2 | $5,904 | +60.5% | 11 | - | $536 | $47,915 | 5 | Walt Disney Pictures | false | false |
| 7 | 5 | Final Destination 5 | $4,626 | +3.1% | 10 | - | $462 | $74,070 | 6 | Warner Bros. | false | false |
| 8 | 7 | Bad Teacher | $3,612 | +6.8% | 6 | - | $602 | $52,408 | 5 | Sony Pictures Releasing | false | false |
| 9 | 8 | Mr. Popper's Penguins | $2,847 | +16.6% | 8 | - | $355 | $51,999 | 7 | 20th Century Fox International | false | false |
| 10 | 9 | Horrible Bosses | $1,809 | +7.9% | 7 | - | $258 | $81,831 | 8 | Warner Bros. | false | false |
| 11 | 11 | Rise of the Planet of the Apes | $901 | +12.2% | 6 | - | $150 | $71,304 | 10 | 20th Century Fox International | false | false |
| 12 | 12 | Zookeeper | $583 | +2.1% | 5 | -2 | $116 | $30,027 | 7 | Sony Pictures Releasing | false | false |
| 13 | 10 | Harry Potter and the Deathly Hallows: Part 2 | $502 | -39.7% | 12 | - | $41 | $273,176 | 13 | Warner Bros. | false | false |
| 14 | 14 | Kung Fu Panda 2 | $191 | -22.7% | 11 | - | $17 | $177,149 | 19 | United International Pictures | false | false |
| 15 | 16 | The Ages of Love | $124 | -6.1% | 2 | - | $62 | $32,421 | 20 | N/A | false | false |
| 16 | 13 | Larry Crowne | $101 | -69.4% | 4 | - | $25 | $11,469 | 6 | N/A | false | false |
