| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Underworld: Awakening | $2,864,463 | - | 214 | - | $13,385 | $2,864,463 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | The Descendants | $2,535,001 | +0.5% | 224 | +7 | $11,316 | $10,182,224 | 3 | 20th Century Fox International | false | false |
| 3 | - | A Few Best Men | $1,955,734 | - | 242 | - | $8,081 | $2,068,507 | 1 | Icon Film Distribution | true | false |
| 4 | 2 | Journey 2: The Mysterious Island | $1,891,114 | -5.5% | 337 | -14 | $5,611 | $5,280,994 | 2 | Warner Bros. | false | false |
| 5 | 8 | Hugo | $1,564,853 | +27.2% | 299 | -69 | $5,233 | $6,555,706 | 3 | Paramount Pictures International | false | false |
| 6 | 3 | Sherlock Holmes: A Game of Shadows | $1,541,691 | -21% | 311 | -51 | $4,957 | $19,216,612 | 4 | Roadshow Films | false | false |
| 7 | 4 | The Muppets | $1,458,722 | -16.2% | 250 | -18 | $5,834 | $8,705,916 | 3 | Walt Disney Pictures | false | false |
| 8 | 6 | Tinker Tailor Soldier Spy | $1,390,980 | -6.8% | 141 | -3 | $9,865 | $3,684,601 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 5 | The Girl with the Dragon Tattoo | $1,192,281 | -21.4% | 249 | -8 | $4,788 | $7,047,921 | 3 | Sony Pictures Releasing | false | false |
| 10 | 7 | Alvin and the Chipmunks: Chipwrecked | $863,620 | -34.8% | 261 | -8 | $3,308 | $19,549,981 | 5 | 20th Century Fox International | false | false |
| 11 | - | J. Edgar | $813,706 | - | 90 | - | $9,041 | $882,276 | 1 | Warner Bros. | true | false |
| 12 | 10 | The Iron Lady | $535,270 | +5.3% | 162 | +26 | $3,304 | $8,859,520 | 5 | Icon Film Distribution | false | false |
| 13 | 9 | The Darkest Hour | $315,936 | -52% | 131 | -25 | $2,411 | $1,317,231 | 2 | 20th Century Fox International | false | false |
| 14 | 12 | War Horse | $312,441 | -32.8% | 127 | -63 | $2,460 | $10,471,706 | 5 | Walt Disney Pictures | false | false |
| 15 | 11 | The Adventures of Tintin | $301,869 | -38.7% | 148 | -145 | $2,039 | $15,731,470 | 5 | Paramount Pictures International | false | false |
| 16 | - | Agneepath | $297,474 | - | 14 | - | $21,248 | $297,474 | 1 | Eros Worldwide | true | false |
| 17 | 14 | Happy Feet Two | $222,619 | -40.6% | 139 | -79 | $1,601 | $11,082,388 | 5 | Roadshow Films | false | false |
| 18 | 13 | Tower Heist | $183,892 | -51.4% | 99 | -50 | $1,857 | $10,533,907 | 5 | Universal Pictures International (UPI) | false | false |
| 19 | 17 | Young Adult | $179,568 | -27.6% | 58 | +1 | $3,096 | $567,761 | 2 | Paramount Pictures International | false | false |
| 20 | 15 | Mission: Impossible - Ghost Protocol | $173,648 | -39.3% | 53 | -91 | $3,276 | $18,554,026 | 7 | Paramount Pictures International | false | false |
