| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Journey 2: The Mysterious Island | $2,953,283 | - | 1,139 | - | $2,592 | $2,953,283 | 1 | Warner Bros. | true | false |
| 2 | 1 | Underworld: Awakening | $1,285,464 | -35% | 464 | -46 | $2,770 | $4,508,986 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | The Girl with the Dragon Tattoo | $586,089 | -31.1% | 486 | -22 | $1,205 | $3,886,371 | 3 | Sony Pictures Releasing | false | false |
| 4 | - | The Descendants | $545,014 | - | 256 | - | $2,128 | $545,014 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | Hugo | $450,509 | -41% | 370 | -7 | $1,217 | $1,555,771 | 2 | Paramount Pictures International | false | false |
| 6 | 4 | Man on a Ledge | $179,049 | -42.9% | 238 | -17 | $752 | $702,914 | 2 | N/A | false | false |
| 7 | 7 | The Ides of March | $134,639 | -43.7% | 78 | +1 | $1,726 | $522,622 | 2 | N/A | false | false |
| 8 | 8 | The Darkest Hour | $132,400 | -43.6% | 227 | -105 | $583 | $3,745,452 | 4 | 20th Century Fox International | false | false |
| 9 | 9 | Drive | $125,920 | -42.6% | 100 | -1 | $1,259 | $489,899 | 2 | Gussi Films | false | false |
| 10 | - | Grave Encounters | $122,841 | - | 90 | - | $1,364 | $122,841 | 1 | N/A | true | false |
| 11 | 12 | A Little Bit of Heaven | $100,987 | -36.9% | 138 | -20 | $731 | $1,839,828 | 6 | N/A | false | false |
| 12 | 5 | Spy Kids 4: All the Time in the World | $99,645 | -67.5% | 254 | -51 | $392 | $1,095,826 | 3 | Gussi Films | false | false |
| 13 | 10 | We Bought a Zoo | $78,220 | -56.8% | 157 | -40 | $498 | $2,604,932 | 7 | 20th Century Fox International | false | false |
| 14 | 6 | Sherlock Holmes: A Game of Shadows | $72,683 | -70.4% | 173 | -222 | $420 | $10,458,972 | 6 | Warner Bros. | false | false |
| 15 | 15 | War Horse | $66,100 | -43.5% | 78 | -21 | $847 | $830,414 | 4 | Walt Disney Pictures | false | false |
| 16 | 14 | Alvin and the Chipmunks: Chipwrecked | $60,223 | -54.2% | 162 | -76 | $371 | $8,203,448 | 8 | 20th Century Fox International | false | false |
| 17 | 29 | Seeking Justice | $55,147 | +454% | 71 | +50 | $776 | $462,224 | 4 | N/A | false | false |
| 18 | 16 | The Ward | $52,704 | -51.5% | 99 | -65 | $532 | $1,439,076 | 5 | Videocine | false | false |
| 19 | 18 | J. Edgar | $48,068 | -41.2% | 73 | -16 | $658 | $1,317,919 | 5 | Warner Bros. | false | false |
| 20 | - | Machine Gun Preacher | $43,617 | - | 50 | - | $872 | $43,617 | 1 | Gussi Films | true | false |
| 21 | 13 | Puss in Boots | $42,512 | -68.6% | 95 | -128 | $447 | $17,537,732 | 10 | Paramount Pictures International | false | false |
| 22 | 17 | The Last Death | $39,559 | -56.5% | 138 | -12 | $286 | $200,266 | 2 | Videocine | false | false |
| 23 | 11 | Mission: Impossible - Ghost Protocol | $38,304 | -76.4% | 113 | -191 | $338 | $12,963,155 | 7 | Paramount Pictures International | false | false |
| 24 | 23 | One Day | $27,240 | -25.8% | 31 | -2 | $878 | $595,359 | 5 | Universal Pictures International (UPI) | false | false |
| 25 | 22 | We Need to Talk About Kevin | $21,066 | -43.8% | 23 | -11 | $915 | $323,066 | 4 | N/A | false | false |
| 26 | 32 | The Rum Diary | $16,754 | +142.6% | 22 | +10 | $761 | $279,026 | 4 | Gussi Films | false | false |
| 27 | 33 | The Conspirator | $16,466 | +228.7% | 32 | +22 | $514 | $188,620 | 6 | Gussi Films | false | false |
| 28 | 25 | New Year's Eve | $10,023 | -68.7% | 24 | -41 | $417 | $2,855,630 | 8 | Warner Bros. | false | false |
| 29 | 28 | Love Life | $9,128 | -10.4% | 20 | +3 | $456 | $122,809 | 5 | N/A | false | false |
| 30 | - | Soul Kitchen | $8,524 | - | 10 | - | $852 | $8,524 | 1 | N/A | true | false |
| 31 | 27 | Sleep Tight | $7,034 | -39.1% | 19 | -18 | $370 | $1,107,633 | 8 | N/A | false | false |
| 32 | 20 | The Adventures of Tintin | $6,696 | -85.6% | 43 | -93 | $155 | $4,207,365 | 7 | Sony Pictures Releasing | false | false |
| 33 | 36 | Kidnapped | $5,038 | +288.1% | 12 | +9 | $419 | $80,239 | 5 | Gussi Films | false | false |
| 34 | 26 | Three Steps Above Heaven | $4,878 | -65.4% | 7 | -43 | $696 | $121,881 | 3 | N/A | false | false |
| 35 | 30 | Immortals | $2,917 | -69.3% | 8 | -15 | $364 | $5,365,813 | 8 | Gussi Films | false | false |
| 36 | 38 | In a Better World | $2,187 | +225% | 6 | +1 | $364 | $106,946 | 7 | N/A | false | false |
| 37 | 41 | Anonymous | $1,323 | +151% | 3 | -1 | $441 | $57,812 | 10 | Sony Pictures Releasing | false | false |
| 38 | 39 | Le Quattro Volte | $579 | -13.3% | 2 | - | $289 | $3,266 | 3 | N/A | false | false |
| 39 | 34 | Arthur Christmas | $172 | -94.3% | 4 | -11 | $43 | $3,365,678 | 9 | Sony Pictures Releasing | false | false |
| 40 | 31 | Exam | $73 | -99.2% | 2 | -33 | $36 | $67,157 | 3 | N/A | false | false |
| 41 | 40 | The Matchmaker | $5 | -99.1% | 1 | -2 | $5 | $2,920 | 3 | N/A | false | false |
