| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Three Fugitives | $5,477,051 | -14.9% | 1,191 | +38 | $4,598 | $13,616,401 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 2 | 1 | Rain Man | $5,449,961 | -20.2% | 1,573 | +10 | $3,464 | $96,278,210 | 8 | Metro-Goldwyn-Mayer (MGM) | false | false |
| 3 | - | Her Alibi | $5,037,047 | - | 1,429 | - | $3,524 | $5,037,047 | 1 | Warner Bros. | true | false |
| 4 | 3 | Beaches | $4,152,096 | -15.9% | 1,109 | +12 | $3,744 | $25,874,160 | 7 | Walt Disney Studios Motion Pictures | false | false |
| 5 | - | Who's Harry Crumb? | $3,862,719 | - | 1,197 | - | $3,227 | $3,862,719 | 1 | TriStar Pictures | true | false |
| 6 | 4 | Twins | $3,348,800 | -30.3% | 1,610 | -49 | $2,080 | $90,796,705 | 9 | Universal Pictures | false | false |
| 7 | 6 | Working Girl | $2,538,140 | -15.5% | 1,133 | -16 | $2,240 | $41,720,209 | 7 | Twentieth Century Fox | false | false |
| 8 | 5 | Mississippi Burning | $2,475,978 | -30.2% | 1,074 | +16 | $2,305 | $18,254,959 | 9 | Orion Pictures | false | false |
| 9 | 7 | The Naked Gun: From the Files of Police Squad! | $1,898,870 | -33.8% | 1,258 | -243 | $1,509 | $70,956,485 | 10 | Paramount Pictures | false | false |
| 10 | 8 | The Accidental Tourist | $1,539,396 | -39.9% | 756 | -170 | $2,036 | $24,017,846 | 7 | Warner Bros. | false | false |
| 11 | 11 | Dangerous Liaisons | $1,134,214 | -12.8% | 119 | - | $9,531 | $6,507,281 | 7 | Warner Bros. | false | false |
| 12 | 10 | Dirty Rotten Scoundrels | $1,049,115 | -35.9% | 1,106 | -207 | $948 | $37,938,092 | 8 | Orion Pictures | false | false |
| 13 | - | Kinjite: Forbidden Subjects | $1,029,058 | - | 320 | - | $3,215 | $1,029,058 | 1 | Cannon Film Distributors | true | false |
| 14 | 9 | Physical Evidence | $618,591 | -65.2% | 695 | +4 | $890 | $2,890,621 | 2 | Columbia Pictures | false | false |
