| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Iron Man | $100,750,000 | $98,618,668 | -$2,131,332 | -2.1% | 4,105 | $104,250,000 | $102,118,668 | 1 | Paramount Pictures | - |
| 2 | 2 | - | Made of Honor | $15,500,000 | $14,756,850 | -$743,150 | -4.8% | 2,729 | $15,500,000 | $14,756,850 | 1 | Sony Pictures Releasing | - |
| 3 | 3 | - | Baby Mama | $10,332,000 | $10,065,010 | -$266,990 | -2.6% | 2,548 | $32,330,000 | $32,062,480 | 2 | Universal Pictures | - |
| 4 | 5 | +1 | Forgetting Sarah Marshall | $6,132,000 | $6,059,920 | -$72,080 | -1.2% | 2,872 | $44,804,000 | $44,732,340 | 3 | Universal Pictures | - |
| 5 | 4 | -1 | Harold & Kumar Escape from Guantanamo Bay | $6,015,000 | $6,114,373 | +$99,373 | +1.7% | 2,545 | $25,270,000 | $25,369,337 | 2 | Warner Bros. | - |
| 6 | 6 | - | The Forbidden Kingdom | $4,200,000 | $4,187,897 | -$12,103 | -0.3% | 2,960 | $45,124,000 | $45,112,303 | 3 | Lionsgate Films | - |
| 7 | 7 | - | Nim's Island | $2,750,000 | $2,677,543 | -$72,457 | -2.6% | 2,478 | $42,544,000 | $42,471,660 | 5 | Twentieth Century Fox | - |
| 8 | 8 | - | Prom Night | $2,500,000 | $2,403,313 | -$96,687 | -3.9% | 2,434 | $41,447,000 | $41,350,731 | 4 | Screen Gems | - |
| 9 | 9 | - | 21 | $2,100,000 | $2,002,471 | -$97,529 | -4.6% | 2,242 | $79,057,000 | $78,959,237 | 6 | Sony Pictures Releasing | - |
| 10 | 10 | - | 88 Minutes | $1,600,000 | $1,545,084 | -$54,916 | -3.4% | 1,765 | $15,424,000 | $15,368,925 | 3 | Sony Pictures Releasing | - |
| 11 | 11 | - | Horton Hears a Who! | $1,350,000 | $1,337,562 | -$12,438 | -0.9% | 1,463 | $149,830,000 | $149,817,680 | 8 | Twentieth Century Fox | - |
| 12 | 12 | - | Deception | $865,000 | $883,417 | +$18,417 | +2.1% | 2,001 | $3,982,000 | $4,000,654 | 2 | Twentieth Century Fox | - |
| 13 | 14 | +1 | Street Kings | $700,000 | $708,142 | +$8,142 | +1.2% | 855 | $25,125,000 | $25,133,327 | 4 | - | - |
| 14 | 15 | +1 | Expelled: No Intelligence Allowed | $684,000 | $678,304 | -$5,696 | -0.8% | 656 | $6,619,000 | $6,613,256 | 3 | Rocky Mountain Pictures | - |
| 15 | 13 | -2 | Drillbit Taylor | $679,000 | $730,231 | +$51,231 | +7.5% | 427 | $31,114,000 | $31,164,888 | 7 | Paramount Pictures | - |
| 16 | 16 | - | The Visitor | $663,000 | $606,597 | -$56,403 | -8.5% | 130 | $1,633,000 | $1,576,256 | 4 | Overture Films | - |
| 17 | 17 | - | Leatherheads | $577,000 | $572,320 | -$4,680 | -0.8% | 1,022 | $30,338,000 | $30,332,745 | 5 | Universal Pictures | - |
| 18 | 19 | +1 | Young@Heart | $330,000 | $315,357 | -$14,643 | -4.4% | 121 | $940,000 | $925,669 | 4 | - | - |
| 19 | 20 | +1 | Shine a Light | $255,000 | $278,006 | +$23,006 | +9% | 142 | $4,823,000 | $4,846,348 | 5 | Paramount Vantage | - |
| 20 | 22 | +2 | The Spiderwick Chronicles | $243,000 | $212,364 | -$30,636 | -12.6% | 287 | $71,180,000 | $71,148,699 | 12 | Paramount Pictures | - |
| 21 | 23 | +2 | The Counterfeiters | $225,000 | $204,303 | -$20,697 | -9.2% | 157 | $4,461,000 | $4,440,307 | 11 | Sony Pictures Classics | - |
| 22 | 21 | -1 | Then She Found Me | $222,000 | $230,461 | +$8,461 | +3.8% | 72 | $316,000 | $353,750 | 2 | THINKFilm | - |
| 23 | 25 | +2 | Under the Same Moon | $209,000 | $193,182 | -$15,818 | -7.6% | 324 | $12,119,000 | $12,102,872 | 7 | The Weinstein Company | - |
| 24 | 24 | - | Superhero Movie | $193,000 | $202,879 | +$9,879 | +5.1% | 463 | $25,254,000 | $25,263,751 | 6 | - | - |
| 25 | 29 | +4 | Meet the Browns | $135,000 | $148,506 | +$13,506 | +10% | 205 | $41,926,000 | $41,939,392 | 7 | Lionsgate Films | - |
| 26 | 30 | +4 | Never Back Down | $132,000 | $145,658 | +$13,658 | +10.3% | 217 | $24,556,000 | $24,569,276 | 8 | Summit Entertainment | - |
| 27 | 34 | +7 | Fugitive Pieces | $108,000 | $102,212 | -$5,788 | -5.4% | 30 | $108,000 | $102,212 | 1 | The Samuel Goldwyn Company | - |
| 28 | 35 | +7 | Priceless | $101,000 | $96,366 | -$4,634 | -4.6% | 44 | $1,258,000 | $1,252,860 | 6 | The Samuel Goldwyn Company | - |
| 29 | 40 | +11 | Miss Pettigrew Lives for a Day | $74,300 | $69,907 | -$4,393 | -5.9% | 136 | $12,155,000 | $12,150,353 | 9 | Focus Features | - |
| 30 | 42 | +12 | The Bank Job | $70,000 | $61,261 | -$8,739 | -12.5% | 101 | $29,742,000 | $29,732,923 | 9 | Lionsgate Films | - |
| 31 | 41 | +10 | Redbelt | $68,600 | $63,361 | -$5,239 | -7.6% | 6 | $68,600 | $63,361 | 1 | Sony Pictures Classics | - |
| 32 | 46 | +14 | In Bruges | $54,900 | $55,260 | +$360 | +0.7% | 71 | $7,488,000 | $7,488,507 | 13 | Focus Features | - |
| 33 | 47 | +14 | Son of Rambow | $52,500 | $53,789 | +$1,289 | +2.5% | 5 | $52,500 | $53,789 | 1 | Paramount Vantage | - |
| 34 | 49 | +15 | My Blueberry Nights | $51,900 | $46,743 | -$5,157 | -9.9% | 52 | $477,000 | $472,087 | 5 | The Weinstein Company | - |
| 35 | 54 | +19 | Stop-Loss | $40,000 | $33,852 | -$6,148 | -15.4% | 52 | $10,857,000 | $10,851,448 | 6 | Paramount Pictures | - |
| 36 | 55 | +19 | Standard Operating Procedure | $33,700 | $31,543 | -$2,157 | -6.4% | 11 | $55,900 | $53,746 | 2 | Sony Pictures Classics | - |
| 37 | 60 | +23 | Penelope | $24,000 | $25,211 | +$1,211 | +5% | 60 | $9,956,000 | $9,956,977 | 10 | Summit Entertainment | - |
| 38 | 66 | +28 | Roman de gare | $24,000 | $22,533 | -$1,467 | -6.1% | 2 | $261,000 | $259,783 | 2 | The Samuel Goldwyn Company | - |
| 39 | 70 | +31 | The Year My Parents Went on Vacation | $23,900 | $18,342 | -$5,558 | -23.3% | 25 | $702,000 | $696,755 | 12 | City Lights Pictures | - |
| 40 | 68 | +28 | Where in the World Is Osama Bin Laden? | $22,500 | $20,964 | -$1,536 | -6.8% | 46 | $309,000 | $307,371 | 3 | The Weinstein Company | - |
| 41 | 69 | +28 | My Brother is an Only Child | $20,200 | $18,977 | -$1,223 | -6.1% | 13 | $122,000 | $121,159 | 6 | THINKFilm | - |
| 42 | 72 | +30 | Mister Lonely | $19,100 | $16,769 | -$2,331 | -12.2% | 1 | $19,100 | $16,769 | 1 | IFC Films | - |
| 43 | 80 | +37 | Deal | $6,000 | $5,926 | -$74 | -1.2% | 51 | $57,300 | $57,180 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 44 | 99 | +55 | Hats Off | $3,500 | $3,238 | -$262 | -7.5% | 5 | $30,000 | $29,759 | 6 | Abramorama | - |
| 45 | 105 | +60 | Never Forever | $2,000 | $2,374 | +$374 | +18.7% | 1 | $13,500 | $13,720 | 4 | Hart Sharp Entertainment | - |
| 46 | 126 | +80 | Pathology | $800 | $787 | -$13 | -1.6% | 3 | $109,000 | $108,662 | 3 | Metro-Goldwyn-Mayer (MGM) | - |
