| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Paul Blart: Mall Cop | $33,800,000 | $31,832,636 | -$1,967,364 | -5.8% | 3,144 | $33,800,000 | $31,832,636 | 1 | Sony Pictures Releasing | - |
| 2 | 2 | - | Gran Torino | $22,235,000 | $21,979,069 | -$255,931 | -1.2% | 2,972 | $73,232,000 | $72,976,480 | 6 | Warner Bros. | - |
| 3 | 3 | - | My Bloody Valentine | $21,900,000 | $21,241,456 | -$658,544 | -3% | 2,534 | $21,900,000 | $21,241,456 | 1 | Lionsgate Films | - |
| 4 | 4 | - | Notorious | $21,500,000 | $20,497,596 | -$1,002,404 | -4.7% | 1,638 | $21,500,000 | $20,497,596 | 1 | - | - |
| 5 | 5 | - | Hotel for Dogs | $17,707,000 | $17,012,212 | -$694,788 | -3.9% | 3,271 | $17,707,000 | $17,012,212 | 1 | DreamWorks | - |
| 6 | 6 | - | Bride Wars | $11,750,000 | $11,651,553 | -$98,447 | -0.8% | 3,228 | $37,577,000 | $37,478,678 | 2 | Twentieth Century Fox | - |
| 7 | 7 | - | The Unborn | $9,849,000 | $9,341,985 | -$507,015 | -5.1% | 2,359 | $33,088,000 | $32,581,140 | 2 | Universal Pictures | - |
| 8 | 8 | - | Defiance | $9,206,000 | $8,911,827 | -$294,173 | -3.2% | 1,789 | $9,547,000 | $9,252,455 | 3 | Paramount Vantage | - |
| 9 | 9 | - | Marley & Me | $6,325,000 | $6,138,859 | -$186,141 | -2.9% | 2,952 | $132,734,000 | $132,548,142 | 4 | Twentieth Century Fox | - |
| 10 | 10 | - | Slumdog Millionaire | $5,900,000 | $5,849,157 | -$50,843 | -0.9% | 582 | $42,737,000 | $42,686,362 | 10 | - | - |
| 11 | 11 | - | The Curious Case of Benjamin Button | $5,599,000 | $5,576,862 | -$22,138 | -0.4% | 2,223 | $102,624,000 | $102,601,599 | 4 | Paramount Pictures | - |
| 12 | 12 | - | Bedtime Stories | $4,848,000 | $4,726,059 | -$121,941 | -2.5% | 2,619 | $103,753,000 | $103,631,350 | 4 | Walt Disney Studios Motion Pictures | - |
| 13 | 13 | - | Last Chance Harvey | $4,655,000 | $4,299,805 | -$355,195 | -7.6% | 1,054 | $5,246,000 | $4,890,722 | 4 | Overture Films | - |
| 14 | 14 | - | Valkyrie | $3,872,000 | $3,802,679 | -$69,321 | -1.8% | 2,007 | $77,592,000 | $77,522,785 | 4 | United Artists | - |
| 15 | 15 | - | Yes Man | $2,705,000 | $2,597,519 | -$107,481 | -4% | 1,704 | $93,660,000 | $93,552,413 | 5 | Warner Bros. | - |
| 16 | 16 | - | Not Easily Broken | $2,100,000 | $1,945,080 | -$154,920 | -7.4% | 725 | $8,244,000 | $8,089,061 | 2 | Screen Gems | - |
| 17 | 19 | +2 | The Wrestler | $1,750,000 | $1,702,695 | -$47,305 | -2.7% | 144 | $5,062,000 | $5,014,663 | 5 | - | - |
| 18 | 17 | -1 | Revolutionary Road | $1,744,000 | $1,783,093 | +$39,093 | +2.2% | 171 | $5,694,000 | $5,733,271 | 4 | Paramount Vantage | - |
| 19 | 18 | -1 | Twilight | $1,743,000 | $1,742,920 | -$80 | <0.1% | 904 | $184,209,000 | $184,208,531 | 9 | Summit Entertainment | - |
| 20 | 21 | +1 | Doubt | $1,325,000 | $1,231,332 | -$93,668 | -7.1% | 725 | $25,357,000 | $25,263,319 | 6 | Miramax | - |
| 21 | 20 | -1 | The Reader | $1,222,000 | $1,285,036 | +$63,036 | +5.2% | 417 | $7,512,000 | $7,575,034 | 6 | The Weinstein Company | - |
| 22 | 22 | - | Seven Pounds | $1,200,000 | $1,215,254 | +$15,254 | +1.3% | 1,121 | $69,157,000 | $69,172,351 | 5 | Sony Pictures Releasing | - |
| 23 | 23 | - | Milk | $764,000 | $778,950 | +$14,950 | +2% | 223 | $20,382,000 | $20,380,174 | 8 | Focus Features | - |
| 24 | 24 | - | The Tale of Despereaux | $722,000 | $713,595 | -$8,405 | -1.2% | 870 | $48,881,000 | $48,872,100 | 5 | Universal Pictures | - |
| 25 | 25 | - | Frost/Nixon | $706,000 | $669,425 | -$36,575 | -5.2% | 153 | $8,665,000 | $8,628,586 | 7 | Universal Pictures | - |
| 26 | 26 | - | CC2C | $651,000 | $629,921 | -$21,079 | -3.2% | 130 | $651,000 | $629,921 | 1 | Warner Bros. | - |
| 27 | 27 | - | Madagascar: Escape 2 Africa | $543,000 | $528,787 | -$14,213 | -2.6% | 334 | $178,110,000 | $178,095,872 | 11 | DreamWorks | - |
| 28 | 28 | - | The Day the Earth Stood Still | $455,000 | $458,634 | +$3,634 | +0.8% | 311 | $78,287,000 | $78,291,000 | 6 | Twentieth Century Fox | - |
| 29 | 32 | +3 | Four Christmases | $269,000 | $263,862 | -$5,138 | -1.9% | 362 | $119,595,000 | $119,589,423 | 8 | Warner Bros. | - |
| 30 | 33 | +3 | Che: Part One/Che: Part Two | $152,000 | $153,175 | +$1,175 | +0.8% | 16 | $477,000 | $477,894 | 6 | IFC Films | - |
| 31 | 36 | +5 | Rachel Getting Married | $124,000 | $102,683 | -$21,317 | -17.2% | 62 | $10,756,000 | $10,734,305 | 16 | Sony Pictures Classics | - |
| 32 | 35 | +3 | Role Models | $108,000 | $104,720 | -$3,280 | -3% | 187 | $67,146,000 | $67,142,910 | 11 | Universal Pictures | - |
| 33 | 38 | +5 | Waltz with Bashir | $84,000 | $78,607 | -$5,393 | -6.4% | 9 | $514,000 | $532,125 | 4 | Sony Pictures Classics | - |
| 34 | 37 | +3 | Vicky Cristina Barcelona | $82,000 | $84,745 | +$2,745 | +3.3% | 88 | $22,936,000 | $22,998,560 | 23 | - | - |
| 35 | 40 | +5 | The Spirit | $60,000 | $74,798 | +$14,798 | +24.7% | 168 | $19,751,000 | $19,765,327 | 4 | Lionsgate Films | - |
| 36 | 44 | +8 | I've Loved You So Long | $47,400 | $42,490 | -$4,910 | -10.4% | 23 | $2,540,000 | $2,535,311 | 13 | Sony Pictures Classics | - |
| 37 | 45 | +8 | Synecdoche, New York | $40,600 | $39,737 | -$863 | -2.1% | 33 | $2,854,000 | $2,853,303 | 13 | Sony Pictures Classics | - |
| 38 | 52 | +14 | Soul Men | $24,500 | $25,764 | +$1,264 | +5.2% | 90 | $12,051,000 | $12,052,391 | 11 | - | - |
| 39 | 55 | +16 | Zack and Miri Make a Porno | $19,000 | $19,366 | +$366 | +1.9% | 50 | $31,430,000 | $31,430,482 | 12 | The Weinstein Company | - |
| 40 | 59 | +19 | Wendy and Lucy | $9,300 | $11,466 | +$2,166 | +23.3% | 4 | $156,000 | $158,653 | 6 | Oscilloscope | - |
