| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | I Can Do Bad All by Myself | $24,030,000 | $23,446,785 | -$583,215 | -2.4% | 2,255 | $24,030,000 | $23,446,785 | 1 | Lionsgate Films | - |
| 2 | 2 | - | 9 | $10,856,000 | $10,740,446 | -$115,554 | -1.1% | 1,661 | $15,264,000 | $15,160,926 | 1 | Focus Features | - |
| 3 | 3 | - | Inglourious Basterds | $6,546,000 | $6,140,617 | -$405,383 | -6.2% | 3,215 | $104,309,000 | $103,903,469 | 4 | The Weinstein Company | - |
| 4 | 4 | - | All About Steve | $5,800,000 | $5,638,243 | -$161,757 | -2.8% | 2,265 | $21,812,000 | $21,650,628 | 2 | Twentieth Century Fox | - |
| 5 | 5 | - | The Final Destination | $5,500,000 | $5,522,377 | +$22,377 | +0.4% | 2,732 | $58,258,000 | $58,280,235 | 3 | Warner Bros. | - |
| 6 | 6 | - | Sorority Row | $5,268,000 | $5,059,802 | -$208,198 | -4% | 2,665 | $5,268,000 | $5,059,802 | 1 | Summit Entertainment | - |
| 7 | 7 | - | Whiteout | $5,100,000 | $4,915,104 | -$184,896 | -3.6% | 2,745 | $5,100,000 | $4,915,104 | 1 | Warner Bros. | - |
| 8 | 8 | - | District 9 | $3,600,000 | $3,538,769 | -$61,231 | -1.7% | 2,560 | $108,517,000 | $108,456,233 | 5 | TriStar Pictures | - |
| 9 | 10 | +1 | Julie & Julia | $3,300,000 | $3,156,316 | -$143,684 | -4.4% | 2,342 | $85,360,000 | $85,216,398 | 6 | Sony Pictures Releasing | - |
| 10 | 9 | -1 | Gamer | $3,150,000 | $3,293,055 | +$143,055 | +4.5% | 2,502 | $16,120,000 | $16,261,653 | 2 | Lionsgate Films | - |
| 11 | 11 | - | G.I. Joe: The Rise of Cobra | $2,525,000 | $2,455,620 | -$69,380 | -2.7% | 2,120 | $144,270,000 | $144,200,266 | 6 | Paramount Pictures | - |
| 12 | 12 | - | The Time Traveler's Wife | $2,325,000 | $2,307,017 | -$17,983 | -0.8% | 2,228 | $59,054,000 | $59,035,745 | 5 | Warner Bros. | - |
| 13 | 14 | +1 | Halloween II | $2,315,000 | $2,114,486 | -$200,514 | -8.7% | 2,350 | $30,295,000 | $30,094,379 | 3 | - | - |
| 14 | 13 | -1 | Extract | $2,233,000 | $2,163,337 | -$69,663 | -3.1% | 1,614 | $8,671,000 | $8,601,746 | 2 | Miramax | - |
| 15 | 15 | - | Shorts | $1,275,000 | $1,211,156 | -$63,844 | -5% | 1,701 | $19,780,000 | $19,716,511 | 4 | Warner Bros. | - |
| 16 | 16 | - | 500 Days of Summer | $1,225,000 | $1,174,165 | -$50,835 | -4.1% | 790 | $30,052,000 | $30,001,366 | 9 | - | - |
| 17 | 17 | - | G-Force | $1,022,000 | $1,015,865 | -$6,135 | -0.6% | 965 | $116,722,000 | $116,715,916 | 8 | Walt Disney Studios Motion Pictures | - |
| 18 | 18 | - | Harry Potter and the Half-Blood Prince | $920,000 | $908,482 | -$11,518 | -1.3% | 744 | $298,856,000 | $298,844,700 | 9 | Warner Bros. | - |
| 19 | 19 | - | The Hangover | $745,000 | $709,225 | -$35,775 | -4.8% | 564 | $273,172,000 | $273,136,280 | 15 | Warner Bros. | - |
| 20 | 20 | - | The September Issue | $730,000 | $693,927 | -$36,073 | -4.9% | 111 | $1,283,000 | $1,266,065 | 3 | Roadside Attractions | - |
| 21 | 21 | - | Ponyo | $656,000 | $628,347 | -$27,653 | -4.2% | 589 | $14,362,000 | $14,333,967 | 5 | Walt Disney Studios Motion Pictures | - |
| 22 | 27 | +5 | Taking Woodstock | $434,000 | $361,728 | -$72,272 | -16.7% | 425 | $7,220,000 | $7,147,708 | 3 | Focus Features | - |
| 23 | 28 | +5 | My One and Only | $406,000 | $350,043 | -$55,957 | -13.8% | 116 | $1,188,000 | $1,131,590 | 4 | Freestyle Releasing | - |
| 24 | 24 | - | Ice Age: Dawn of the Dinosaurs | $400,000 | $375,176 | -$24,824 | -6.2% | 353 | $194,695,000 | $194,670,074 | 11 | Twentieth Century Fox | - |
| 25 | 25 | - | The Ugly Truth | $380,000 | $373,287 | -$6,713 | -1.8% | 385 | $88,151,000 | $88,144,623 | 8 | Sony Pictures Releasing | - |
| 26 | 26 | - | Transformers: Revenge of the Fallen | $350,000 | $370,040 | +$20,040 | +5.7% | 406 | $401,107,000 | $401,127,275 | 12 | DreamWorks | - |
| 27 | 29 | +2 | Aliens in the Attic | $345,000 | $343,788 | -$1,212 | -0.4% | 392 | $24,167,000 | $24,165,755 | 7 | Twentieth Century Fox | - |
| 28 | 30 | +2 | Star Trek | $200,000 | $190,314 | -$9,686 | -4.8% | 234 | $257,434,000 | $257,424,306 | 19 | Paramount Pictures | - |
| 29 | 31 | +2 | Adam | $147,000 | $141,638 | -$5,362 | -3.6% | 121 | $2,014,000 | $2,008,282 | 7 | - | - |
| 30 | 35 | +5 | It Might Get Loud | $142,000 | $127,282 | -$14,718 | -10.4% | 61 | $802,000 | $786,813 | 5 | Sony Pictures Classics | - |
| 31 | 32 | +1 | The Hurt Locker | $141,000 | $141,017 | +$17 | <0.1% | 187 | $12,264,000 | $12,263,550 | 12 | Summit Entertainment | - |
| 32 | 36 | +4 | Night at the Museum: Battle of the Smithsonian | $112,000 | $107,573 | -$4,427 | -4% | 162 | $176,929,000 | $176,924,618 | 17 | Twentieth Century Fox | - |
| 33 | 38 | +5 | A Perfect Getaway | $91,000 | $88,030 | -$2,970 | -3.3% | 142 | $15,486,000 | $15,483,540 | 6 | Universal Pictures | - |
| 34 | 39 | +5 | Funny People | $89,000 | $87,870 | -$1,130 | -1.3% | 174 | $51,815,000 | $51,814,190 | 7 | Universal Pictures | - |
| 35 | 41 | +6 | The Goods: Live Hard, Sell Hard | $75,000 | $75,330 | +$330 | +0.4% | 150 | $15,000,000 | $15,000,327 | 5 | Paramount Vantage | - |
| 36 | 44 | +8 | The Other Man | $56,600 | $51,909 | -$4,691 | -8.3% | 8 | $56,600 | $51,909 | 1 | Image Entertainment | - |
| 37 | 46 | +9 | Bandslam | $50,000 | $48,677 | -$1,323 | -2.6% | 153 | $5,159,000 | $5,157,620 | 5 | Summit Entertainment | - |
| 38 | 54 | +16 | Broken Hill | $41,300 | $32,140 | -$9,160 | -22.2% | 48 | $41,300 | $32,140 | 1 | - | - |
| 39 | 49 | +10 | Big Fan | $39,000 | $35,884 | -$3,116 | -8% | 13 | $108,000 | $105,339 | 3 | First Independent Pictures | - |
| 40 | 53 | +13 | Amreeka | $32,700 | $32,890 | +$190 | +0.6% | 4 | $116,000 | $115,897 | 2 | National Geographic Entertainment | - |
| 41 | 59 | +18 | The Cove | $23,800 | $24,005 | +$205 | +0.9% | 29 | $726,000 | $726,699 | 7 | Roadside Attractions | - |
| 42 | 66 | +24 | No Impact Man: The Documentary | $17,500 | $15,215 | -$2,285 | -13.1% | 2 | $17,500 | $15,215 | 1 | Oscilloscope | - |
| 43 | 64 | +21 | Crude | $16,700 | $16,595 | -$105 | -0.6% | 1 | $22,000 | $21,823 | 1 | First Run | - |
| 44 | 70 | +26 | Tetro | $13,200 | $11,845 | -$1,355 | -10.3% | 12 | $494,000 | $492,506 | 14 | American Zoetrope | - |
| 45 | 84 | +39 | Walt & El Grupo | $6,300 | $6,059 | -$241 | -3.8% | 3 | $7,400 | $7,164 | 1 | Walt Disney Studios Motion Pictures | - |
