| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Prestige | $1,149,140 | - | 250 | - | $4,596 | $1,341,233 | 2 | Warner Bros. | false | false |
| 2 | 1 | Barnyard | $1,085,651 | -28.9% | 385 | - | $2,819 | $2,603,578 | 2 | United International Pictures | false | false |
| 3 | - | The Grudge 2 | $840,035 | - | 216 | - | $3,889 | $1,012,674 | 2 | Gussi Films | false | false |
| 4 | 2 | Pan's Labyrinth | $758,260 | -28.7% | 187 | -3 | $4,054 | $2,957,536 | 3 | Warner Bros. | false | false |
| 5 | 5 | The Illusionist | $754,297 | -21.3% | 250 | - | $3,017 | $5,660,834 | 6 | Videocine | false | false |
| 6 | 3 | Open Season | $626,989 | -40.9% | 436 | -155 | $1,438 | $6,381,986 | 5 | Sony Pictures Releasing | false | false |
| 7 | 4 | The Covenant | $582,530 | -42.6% | 292 | -8 | $1,994 | $1,591,505 | 2 | Sony Pictures Releasing | false | false |
| 8 | 6 | The Guardian | $440,293 | -54% | 340 | -60 | $1,294 | $2,895,202 | 3 | Buena Vista International | false | false |
| 9 | 7 | Volver | $282,426 | -39% | 183 | -17 | $1,543 | $742,875 | 2 | 20th Century Fox International | false | false |
| 10 | 8 | The Devil Wears Prada | $141,337 | -46.7% | 93 | -73 | $1,519 | $5,659,405 | 7 | 20th Century Fox International | false | false |
| 11 | 9 | Lucky Number Slevin | $118,880 | -44.2% | 72 | -4 | $1,651 | $330,686 | 2 | Gussi Films | false | false |
| 12 | 10 | Ugly Me | $112,986 | -38.1% | 95 | -70 | $1,189 | $2,109,037 | 5 | United International Pictures | false | false |
| 13 | 13 | World Trade Center | $108,576 | -15.2% | 84 | -7 | $1,292 | $5,158,774 | 8 | United International Pictures | false | false |
| 14 | 11 | Open Water 2: Adrift | $98,791 | -30.1% | 92 | -38 | $1,073 | $1,201,086 | 5 | Videocine | false | false |
| 15 | 18 | Elsa & Fred | $82,356 | +46.9% | 50 | +28 | $1,647 | $757,639 | 14 | Zima Entertainment | false | false |
| 16 | 19 | A Sound of Thunder | $71,502 | +55.5% | 45 | +13 | $1,588 | $415,515 | 5 | Gussi Films | false | false |
| 17 | - | Opal Dream | $61,862 | - | 102 | - | $606 | $80,569 | 2 | Azteca Films | false | false |
| 18 | 12 | Little Man | $57,956 | -54.9% | 55 | -75 | $1,053 | $5,340,605 | 9 | Sony Pictures Releasing | false | false |
| 19 | 14 | United 93 | $54,202 | -45.9% | 54 | -17 | $1,003 | $2,390,423 | 12 | United International Pictures | false | false |
| 20 | - | Step Up | $51,442 | - | 47 | - | $1,094 | $396,074 | 4 | Videocine | false | false |
