| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Blood Diamond | $419,573 | - | 65 | - | $6,454 | $445,461 | 2 | Warner Bros. | false | false |
| 2 | 2 | The Pursuit of Happyness | $230,652 | -30.8% | 52 | - | $4,435 | $562,604 | 3 | Sony Pictures Releasing | false | false |
| 3 | 1 | John Tucker Must Die | $211,277 | -38.7% | 47 | - | $4,495 | $565,101 | 3 | - | false | false |
| 4 | - | Arthur and the Invisibles | $142,527 | - | 51 | - | $2,794 | $142,527 | 2 | Constantin Film | false | false |
| 5 | 6 | Babel | $126,484 | -17.9% | 20 | - | $6,324 | $1,029,507 | 7 | Constantin Film | false | false |
| 6 | 4 | The Queen | $122,219 | -25.2% | 26 | - | $4,700 | $474,027 | 4 | Filmladen | false | false |
| 7 | 8 | My Führer | $119,945 | -12.9% | 34 | +15 | $3,527 | $257,067 | 3 | Filmladen | false | false |
| 8 | 5 | Charlotte's Web | $94,923 | -39.6% | 61 | - | $1,556 | $424,222 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | - | One Way | $66,616 | - | 38 | - | $1,753 | $66,616 | 2 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | The Holiday | $66,378 | -53.2% | 61 | -23 | $1,088 | $2,779,811 | 8 | United International Pictures | false | false |
| 11 | - | Masked Gang: Iraq | $51,708 | - | 8 | - | $6,463 | $53,242 | 2 | Maxximum Film und Kunst GmbH | false | false |
| 12 | 11 | The Departed | $45,836 | -49.9% | 57 | -8 | $804 | $2,022,239 | 9 | Warner Bros. | false | false |
| 13 | 13 | Grave Decisions | $45,421 | -36.1% | 30 | - | $1,514 | $683,787 | 12 | Luna Filmverleih | false | false |
| 14 | 10 | The Texas Chainsaw Massacre: The Beginning | $44,914 | -52.7% | 16 | - | $2,807 | $139,530 | 3 | Warner Bros. | false | false |
| 15 | 9 | Deja Vu | $44,713 | -60.2% | 64 | -11 | $698 | $1,278,532 | 6 | Buena Vista International | false | false |
| 16 | 3 | Night at the Museum | $36,947 | -86.5% | 45 | -43 | $821 | $2,627,235 | 6 | - | false | false |
| 17 | 12 | The Prestige | $31,809 | -57.8% | 24 | - | $1,325 | $485,513 | 5 | Warner Bros. | false | false |
| 18 | - | A Prairie Home Companion | $31,797 | - | 9 | - | $3,533 | $31,797 | 2 | Polyfilm Verleih | false | false |
| 19 | 15 | Casino Royale | $29,958 | -43.8% | 35 | -11 | $855 | $5,788,572 | 11 | Sony Pictures Releasing | false | false |
| 20 | 16 | Flushed Away | $26,383 | -39.8% | 71 | -3 | $371 | $1,252,358 | 9 | United International Pictures | false | false |
