| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | KM 31: Kilometre 31 | $1,468,895 | -2.6% | 275 | - | $5,341 | $4,345,589 | 2 | Videocine | false | false |
| 2 | - | Blood Diamond | $1,073,712 | - | 350 | - | $3,067 | $1,075,283 | 1 | Warner Bros. | true | false |
| 3 | 3 | The Pursuit of Happyness | $1,048,580 | -21.6% | 303 | - | $3,460 | $3,389,103 | 2 | Sony Pictures Releasing | false | false |
| 4 | 2 | Apocalypto | $659,267 | -50.7% | 371 | - | $1,777 | $6,689,824 | 3 | 20th Century Fox International | false | false |
| 5 | 5 | Perfume: The Story of a Murderer | $284,430 | -26.6% | 199 | -1 | $1,429 | $3,530,392 | 4 | Gussi Films | false | false |
| 6 | 4 | Night at the Museum | $283,195 | -36.7% | 298 | -52 | $950 | $19,030,044 | 8 | 20th Century Fox International | false | false |
| 7 | 6 | Pan's Labyrinth | $182,718 | -16.3% | 120 | -14 | $1,522 | $5,532,491 | 17 | Warner Bros. | false | false |
| 8 | - | Employee of the Month | $167,743 | - | 148 | - | $1,133 | $167,743 | 1 | Videocine | true | false |
| 9 | 7 | The Holiday | $162,840 | -18% | 147 | -31 | $1,107 | $3,050,623 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | 8 | Rocky Balboa | $147,881 | -16.4% | 170 | -76 | $869 | $4,654,850 | 5 | 20th Century Fox International | false | false |
| 11 | 10 | Fuera del cielo | $100,626 | -23.4% | 158 | +11 | $636 | $2,626,678 | 5 | Videocine | false | false |
| 12 | 9 | Babel | $83,326 | -48.1% | 101 | -44 | $825 | $7,176,573 | 14 | United International Pictures | false | false |
| 13 | 20 | Stormbreaker | $68,878 | +58.4% | 76 | +8 | $906 | $905,354 | 6 | Azteca Films | false | false |
| 14 | - | The Long Weekend | $61,210 | - | 95 | - | $644 | $321,468 | 4 | Videocine | false | false |
| 15 | 17 | The Wicker Man | $60,332 | +22.7% | 57 | +17 | $1,058 | $1,189,193 | 14 | Gussi Films | false | false |
| 16 | - | The Last King of Scotland | $57,365 | - | 18 | - | $3,186 | $57,365 | 1 | 20th Century Fox International | true | false |
| 17 | 13 | Unaccompanied Minors | $47,506 | -33.8% | 51 | -24 | $931 | $1,378,346 | 8 | Warner Bros. | false | false |
| 18 | 12 | Dreamgirls | $46,246 | -49.8% | 75 | -38 | $616 | $537,288 | 3 | Paramount Pictures International | false | false |
| 19 | 11 | Tired of Kissing Frogs | $43,500 | -66.2% | 71 | -74 | $612 | $6,633,548 | 9 | Buena Vista International | false | false |
| 20 | 18 | Saint Ange 2006 Re-release | $39,903 | -16.6% | 43 | -16 | $927 | $728,018 | 7 | Gussi Films | false | false |
