| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Who Says It's Easy? | $128,331 | -28.7% | 54 | - | $2,376 | $939,987 | 5 | Primer Plano Film Group | false | false |
| 2 | 3 | The Queen | $108,243 | -38.7% | 34 | +2 | $3,183 | $520,369 | 3 | Distribution Company | false | false |
| 3 | - | Norbit | $103,169 | - | 30 | - | $3,438 | $103,169 | 1 | United International Pictures | true | false |
| 4 | 5 | Babel | $88,313 | -28.8% | 47 | - | $1,879 | $1,580,228 | 8 | United International Pictures | false | false |
| 5 | 4 | Night at the Museum | $83,495 | -47.4% | 82 | -9 | $1,018 | $3,079,882 | 8 | 20th Century Fox International | false | false |
| 6 | - | Notes on a Scandal | $81,755 | - | 20 | - | $4,087 | $81,755 | 1 | 20th Century Fox International | true | false |
| 7 | 1 | Rocky Balboa | $81,433 | -59.3% | 38 | +1 | $2,142 | $280,945 | 2 | 20th Century Fox International | false | false |
| 8 | - | Stranger Than Fiction | $79,940 | - | 14 | - | $5,710 | $79,940 | 1 | Sony Pictures Releasing | true | false |
| 9 | - | Crank | $79,751 | - | 27 | - | $2,953 | $79,751 | 1 | Alfa Films | true | false |
| 10 | 6 | Blood Diamond | $76,277 | -37.5% | 45 | +1 | $1,695 | $728,644 | 5 | Warner Bros. | false | false |
| 11 | - | The Wicker Man | $71,503 | - | 20 | - | $3,575 | $71,503 | 1 | Distribution Company | true | false |
| 12 | 7 | The Good Shepherd | $58,472 | -45.4% | 40 | -1 | $1,461 | $327,136 | 3 | United International Pictures | false | false |
| 13 | 10 | Apocalypto | $56,985 | -30.1% | 29 | - | $1,965 | $643,739 | 6 | 20th Century Fox International | false | false |
| 14 | 8 | The Departed | $49,888 | -51.3% | 43 | -9 | $1,160 | $1,999,945 | 17 | Warner Bros. | false | false |
| 15 | 9 | Hoodwinked! | $45,038 | -52.8% | 44 | - | $1,023 | $708,679 | 5 | Alfa Films | false | false |
| 16 | 11 | Deja Vu | $27,277 | -47.3% | 43 | -8 | $634 | $1,808,969 | 10 | Buena Vista International | false | false |
| 17 | 12 | Letters from Iwo Jima | $24,193 | -47.4% | 14 | - | $1,728 | $232,468 | 4 | Warner Bros. | false | false |
| 18 | 13 | Perfume: The Story of a Murderer | $20,582 | -51.7% | 20 | -4 | $1,029 | $229,587 | 4 | Distribution Company | false | false |
| 19 | 17 | The Last King of Scotland | $15,922 | -27.9% | 14 | - | $1,137 | $101,376 | 4 | 20th Century Fox International | false | false |
| 20 | 15 | Borat | $15,490 | -48.3% | 12 | -6 | $1,290 | $241,794 | 5 | 20th Century Fox International | false | false |
