| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 300 | $349,847 | -42.9% | 64 | -12 | $5,466 | $966,333 | 2 | Warner Bros. | false | false |
| 2 | - | Meet the Robinsons | $148,818 | - | 39 | - | $3,815 | $148,818 | 1 | Buena Vista International | true | false |
| 3 | - | The Reaping | $119,948 | - | 31 | - | $3,869 | $119,948 | 1 | Warner Bros. | true | false |
| 4 | - | Ghost Rider | $118,430 | - | 36 | - | $3,289 | $118,430 | 1 | Sony Pictures Releasing | true | false |
| 5 | - | TMNT | $86,104 | - | 26 | - | $3,311 | $86,104 | 1 | Bazuca Films | true | false |
| 6 | - | Mr. Bean's Holiday | $79,532 | - | 25 | - | $3,181 | $79,532 | 1 | United International Pictures | true | false |
| 7 | 4 | Music and Lyrics | $19,379 | -40.5% | 12 | -12 | $1,614 | $157,852 | 4 | Warner Bros. | false | false |
| 8 | 3 | Apocalypto | $19,322 | -43.3% | 13 | -6 | $1,486 | $285,329 | 5 | 20th Century Fox International | false | false |
| 9 | 7 | Curse of the Golden Flower | $18,084 | -28.2% | 11 | - | $1,644 | $90,984 | 3 | Sony Pictures Releasing | false | false |
| 10 | 6 | Captain Alatriste: The Spanish Musketeer | $13,344 | -50.8% | 10 | - | $1,334 | $40,635 | 2 | 20th Century Fox International | false | false |
| 11 | 2 | Arthur and the Invisibles | $12,199 | -76.6% | 18 | -5 | $677 | $159,293 | 4 | Bazuca Films | false | false |
| 12 | 8 | Borat | $10,730 | -45.6% | 5 | -3 | $2,146 | $108,054 | 4 | 20th Century Fox International | false | false |
| 13 | 10 | Pan's Labyrinth | $10,054 | -34.1% | 10 | +1 | $1,005 | $215,532 | 7 | Warner Bros. | false | false |
| 14 | 13 | Breaking and Entering | $7,060 | -23% | 2 | - | $3,530 | $16,297 | 2 | Buena Vista International | false | false |
| 15 | 9 | The Holiday | $6,562 | -65.8% | 5 | -9 | $1,312 | $283,367 | 7 | United International Pictures | false | false |
| 16 | - | Norbit | $6,083 | - | 6 | - | $1,013 | $123,780 | 5 | United International Pictures | false | false |
| 17 | 14 | Notes on a Scandal | $4,459 | -44.3% | 2 | -1 | $2,229 | $99,524 | 6 | 20th Century Fox International | false | false |
| 18 | 5 | Night at the Museum | $4,304 | -86.4% | 11 | -21 | $391 | $1,893,724 | 12 | 20th Century Fox International | false | false |
| 19 | 12 | The Pursuit of Happyness | $2,760 | -71.8% | 4 | -6 | $690 | $232,506 | 9 | Sony Pictures Releasing | false | false |
| 20 | 18 | Deja Vu | $1,340 | -40% | 1 | - | $1,340 | $327,384 | 13 | Buena Vista International | false | false |
| 21 | 16 | The Last King of Scotland | $746 | -84.7% | 1 | -3 | $746 | $102,138 | 8 | 20th Century Fox International | false | false |
| 22 | 17 | Letters from Iwo Jima | $303 | -91.8% | 1 | -6 | $303 | $144,948 | 8 | Warner Bros. | false | false |
| 23 | 19 | Happy Feet | $171 | -89.1% | 2 | -1 | $85 | $825,451 | 19 | Warner Bros. | false | false |
| 24 | 21 | Ice Age: The Meltdown | $91 | -12.5% | 1 | - | $91 | $3,605,634 | 54 | N/A | false | false |
| 25 | 22 | Garfield: A Tail of Two Kitties | $88 | +214.3% | 1 | - | $88 | $766,641 | 38 | 20th Century Fox International | false | false |
| 26 | 20 | A Movie of Eggs | $67 | -86.5% | 1 | -2 | $67 | $60,484 | 13 | Warner Bros. | false | false |
