| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Rain Man | $6,854,993 | -22.6% | 1,573 | +10 | $4,357 | $97,683,242 | 8 | Metro-Goldwyn-Mayer (MGM) | false | false |
| 2 | 2 | Three Fugitives | $6,820,149 | -16.2% | 1,191 | +38 | $5,726 | $14,959,499 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 3 | - | Her Alibi | $6,247,278 | - | 1,429 | - | $4,371 | $6,247,278 | 1 | Warner Bros. | true | false |
| 4 | 3 | Beaches | $5,458,053 | -16.3% | 1,109 | +12 | $4,921 | $27,180,117 | 7 | Walt Disney Studios Motion Pictures | false | false |
| 5 | - | Who's Harry Crumb? | $4,671,081 | - | 1,197 | - | $3,902 | $4,671,081 | 1 | TriStar Pictures | true | false |
| 6 | 4 | Twins | $4,071,490 | -29% | 1,609 | -50 | $2,530 | $91,519,395 | 9 | Universal Pictures | false | false |
| 7 | 6 | Working Girl | $3,208,850 | -18.8% | 1,133 | -16 | $2,832 | $42,390,919 | 7 | Twentieth Century Fox | false | false |
| 8 | 5 | Mississippi Burning | $3,188,391 | -30.7% | 1,074 | +16 | $2,968 | $18,967,372 | 9 | Orion Pictures | false | false |
| 9 | 7 | The Naked Gun: From the Files of Police Squad! | $2,340,798 | -34.2% | 1,258 | -243 | $1,860 | $71,398,413 | 10 | Paramount Pictures | false | false |
| 10 | 8 | The Accidental Tourist | $1,895,969 | -40.7% | 756 | -170 | $2,507 | $24,374,419 | 7 | Warner Bros. | false | false |
| 11 | 11 | Dangerous Liaisons | $1,488,576 | -16.1% | 119 | - | $12,509 | $6,861,643 | 7 | Warner Bros. | false | false |
| 12 | 10 | Dirty Rotten Scoundrels | $1,383,818 | -33.8% | 1,106 | -207 | $1,251 | $38,272,795 | 8 | Orion Pictures | false | false |
| 13 | - | Kinjite: Forbidden Subjects | $1,312,436 | - | 320 | - | $4,101 | $1,312,436 | 1 | Cannon Film Distributors | true | false |
