| TW | LW | Total | %± LW | Share | Releases | #1 Release
| Gross | % of Total | Week | Distributor
| New This Week
|
|---|
| 1 | 1 | $63,499,887 | -26.4% | 30.1% | 8 | The Hangover | $54,089,440 | 85.2% | 2 | Warner Bros. | - |
| 2 | 2 | $46,828,118 | -27.5% | 22.2% | 6 | Up | $46,112,546 | 98.5% | 3 | Walt Disney Studios Motion Pictures | - |
| 3 | 6 | $38,270,743 | +303.9% | 18.2% | 2 | The Taking of Pelham 123 | $32,032,325 | 83.7% | 1 | Sony Pictures Releasing | - |
| 4 | 3 | $20,260,085 | -44.8% | 9.6% | 4 | Land of the Lost | $13,870,045 | 68.5% | 2 | Universal Pictures | - |
| 5 | 5 | $17,617,335 | +19.1% | 8.4% | 3 | Star Trek | $8,315,504 | 47.2% | 6 | Paramount Pictures | - |
| 6 | 4 | $16,268,471 | -32.2% | 7.7% | 3 | Night at the Museum: Battle of the Smithsonian | $14,805,754 | 91% | 4 | Twentieth Century Fox | - |
| 7 | 7 | $2,699,771 | -42.1% | 1.3% | 1 | My Life in Ruins | $2,699,771 | 100% | 2 | - | - |
| 8 | 10 | $1,062,602 | +43.4% | 0.5% | 10 | Easy Virtue | $441,014 | 41.5% | 4 | Sony Pictures Classics | - |
| 9 | 12 | $956,999 | +197.2% | 0.5% | 4 | Away We Go | $869,069 | 90.8% | 2 | Focus Features | - |
| 10 | 8 | $703,105 | -24.8% | 0.3% | 3 | The Brothers Bloom | $450,824 | 64.1% | 5 | Summit Entertainment | - |
| 11 | 9 | $582,896 | -29.2% | 0.3% | 2 | Monsters vs. Aliens | $332,925 | 57.1% | 12 | DreamWorks | - |
| 12 | 13 | $236,350 | -17.4% | 0.1% | 3 | Summer Hours | $181,522 | 76.8% | 5 | IFC Films | - |
| 13 | 15 | $210,965 | +33.8% | 0.1% | 7 | Food, Inc. | $97,726 | 46.3% | 1 | Magnolia Pictures | - |
| 14 | 14 | $206,856 | +17.1% | <0.1% | 12 | Departures | $143,280 | 69.3% | 3 | Regent Releasing | - |
| 15 | 16 | $167,097 | +56.3% | <0.1% | 4 | Magnificent Desolation: Walking on the Moon | $79,966 | 47.9% | 195 | IMAX | - |
| 16 | 20 | $131,836 | +76% | <0.1% | 1 | Sunshine Cleaning | $131,836 | 100% | 14 | Overture Films | - |
| 17 | 11 | $121,807 | -66.7% | <0.1% | 1 | Obsessed | $121,807 | 100% | 8 | Screen Gems | - |
| 18 | 18 | $95,778 | +6.5% | <0.1% | 1 | Valentino: The Last Emperor | $95,778 | 100% | 14 | Truly Indie | - |
| 19 | 19 | $74,235 | -15.8% | <0.1% | 3 | Seraphine | $59,097 | 79.6% | 2 | Music Box Films | - |
| 21 | 22 | $60,780 | +6.3% | <0.1% | 1 | Dolphins and Whales 3D: Tribes of the Ocean | $60,780 | 100% | 70 | 3D Entertainment | - |
| 22 | 17 | $52,261 | -50.8% | <0.1% | 1 | Is Anybody There? | $52,261 | 100% | 9 | - | - |
| 23 | 21 | $49,981 | -21.3% | <0.1% | 3 | Goodbye Solo | $49,744 | 99.5% | 12 | Roadside Attractions | - |
| 24 | 36 | $48,986 | +617.2% | <0.1% | 1 | Tetro | $48,986 | 100% | 2 | American Zoetrope | - |
| 26 | 24 | $41,695 | +10.8% | <0.1% | 2 | The Merry Gentleman | $21,733 | 52.1% | 7 | The Samuel Goldwyn Company | - |
| 27 | 23 | $40,135 | -6.3% | <0.1% | 2 | Sea Monsters: A Prehistoric Adventure | $26,813 | 66.8% | 89 | National Geographic Entertainment | - |
| 28 | 26 | $30,449 | -4.7% | <0.1% | 1 | Anvil | $30,449 | 100% | 10 | Abramorama | - |
| 29 | 27 | $28,862 | +30.4% | <0.1% | 3 | Unmistaken Child | $25,851 | 89.6% | 3 | Oscilloscope | - |
| 30 | 25 | $25,950 | -26.4% | <0.1% | 1 | Revanche | $25,950 | 100% | 7 | Janus Films | - |
| 31 | 28 | $25,140 | +23.1% | <0.1% | 4 | Tulpan | $12,327 | 49% | 12 | Zeitgeist Films | - |
| 34 | 35 | $19,650 | +112.6% | <0.1% | 1 | Herb & Dorothy | $19,650 | 100% | 2 | Arthouse Films | - |
| 35 | 31 | $19,020 | +24.8% | <0.1% | 2 | Call of the Wild | $17,980 | 94.5% | 1 | Vivendi Entertainment | - |
| 37 | 33 | $18,028 | +29.1% | <0.1% | 1 | Lymelife | $18,028 | 100% | 11 | Screen Media Films | - |
| 38 | 30 | $14,722 | -6.6% | <0.1% | 1 | Enlighten Up! | $14,722 | 100% | 40 | Balcony Releasing | - |
| 39 | 34 | $12,142 | +2.5% | <0.1% | 3 | Stomp! Shout! Scream! | $5,390 | 44.4% | 10 | Indican Pictures | - |
| 40 | 32 | $7,541 | -46.1% | <0.1% | 2 | 24 City | $6,961 | 92.3% | 2 | The Cinema Guild | - |
| 41 | 38 | $6,763 | +4.3% | <0.1% | 1 | Pressure Cooker | $6,763 | 100% | 4 | - | - |
| 42 | 42 | $6,143 | +138.8% | <0.1% | 2 | Sleep Dealer | $6,143 | 100% | 9 | Maya Entertainment | - |
| 43 | 37 | $6,103 | -7.5% | <0.1% | 1 | Harvard Beats Yale 29-29 | $6,103 | 100% | 31 | Kino International | - |
| 44 | 29 | $5,668 | -64.6% | <0.1% | 3 | Downloading Nancy | $5,023 | 88.6% | 2 | Strand Releasing | - |
| 46 | 39 | $4,018 | -34.6% | <0.1% | 1 | Throw Down Your Heart | $4,018 | 100% | 14 | Argot Pictures | - |
| 47 | 50 | $3,675 | +4,672.7% | <0.1% | 1 | Home | $3,675 | 100% | 9 | Monterey Media | - |
| 49 | 46 | $2,919 | +305.4% | <0.1% | 2 | A Wink and a Smile | $1,662 | 56.9% | 7 | First Run | - |
| 50 | 49 | $1,340 | +1,422.7% | <0.1% | 1 | In a Dream | $1,340 | 100% | 10 | International Film Circuit | - |
| 51 | 43 | $1,108 | -17.6% | <0.1% | 1 | Tokyo! | $1,108 | 100% | 15 | Liberation Entertainment | - |
| 52 | 41 | $843 | -73.2% | <0.1% | 1 | Gigantic | $843 | 100% | 11 | First Independent Pictures | - |
| 54 | 45 | $347 | -54.8% | <0.1% | 1 | Not Forgotten | $347 | 100% | 7 | Anchor Bay Films | - |
| 55 | 48 | $126 | -48.1% | <0.1% | 1 | Battle for Terra | $126 | 100% | 7 | Lionsgate Films | - |
