| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Uncle Buck | $9,959,005 | -41.2% | 1,835 | +31 | $5,427 | $26,904,176 | 2 | Universal Pictures | false | false |
| 2 | 2 | Parenthood | $9,283,590 | -20.4% | 1,376 | +56 | $6,746 | $56,608,186 | 5 | Universal Pictures | false | false |
| 3 | 3 | The Abyss | $6,965,958 | -34.9% | 1,525 | -13 | $4,567 | $35,194,856 | 3 | Twentieth Century Fox | false | false |
| 4 | 5 | When Harry Met Sally... | $6,066,942 | -18.9% | 1,171 | +27 | $5,180 | $62,666,074 | 7 | Columbia Pictures | false | false |
| 5 | 6 | Lethal Weapon 2 | $4,922,985 | -26.1% | 1,560 | -24 | $3,155 | $126,643,278 | 8 | Warner Bros. | false | false |
| 6 | 7 | Turner & Hooch | $4,461,227 | -31.4% | 1,551 | -43 | $2,876 | $53,320,230 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 7 | 4 | Casualties of War | $4,175,018 | -45.6% | 1,487 | - | $2,807 | $11,853,448 | 2 | Columbia Pictures | false | false |
| 8 | 8 | Batman | $3,964,104 | -26.2% | 1,302 | -98 | $3,044 | $235,019,740 | 10 | Warner Bros. | false | false |
| 9 | 11 | Honey, I Shrunk the Kids | $2,652,667 | -23.8% | 1,189 | +31 | $2,231 | $116,336,941 | 10 | Walt Disney Studios Motion Pictures | false | false |
| 10 | - | The Package | $2,598,395 | - | 323 | - | $8,044 | $2,598,395 | 1 | Orion Pictures | true | false |
| 11 | - | Millennium | $2,248,409 | - | 486 | - | $4,626 | $2,248,409 | 1 | Twentieth Century Fox | true | false |
| 12 | 9 | A Nightmare on Elm Street: The Dream Child | $2,090,619 | -56.9% | 1,114 | -732 | $1,876 | $18,044,399 | 3 | New Line Cinema | false | false |
| 13 | 17 | Sex, Lies, and Videotape | $2,059,830 | +62.6% | 101 | +61 | $20,394 | $4,647,830 | 4 | Miramax | false | false |
| 14 | 10 | Cheetah | $1,876,221 | -55.8% | 1,321 | +11 | $1,420 | $6,122,176 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 15 | 13 | Lock Up | $1,575,827 | -35.3% | 829 | -203 | $1,900 | $17,602,284 | 4 | TriStar Pictures | false | false |
| 16 | 15 | Dead Poets Society | $1,447,684 | -10.3% | 671 | +38 | $2,157 | $85,032,060 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 17 | 12 | Let It Ride | $1,431,363 | -50.3% | 1,191 | - | $1,201 | $4,311,201 | 2 | Paramount Pictures | false | false |
| 18 | 16 | Indiana Jones and the Last Crusade | $1,089,348 | -32.1% | 431 | -80 | $2,527 | $186,838,247 | 15 | Paramount Pictures | false | false |
| 19 | 18 | Ghostbusters II | $990,954 | -21.4% | 606 | -19 | $1,635 | $109,344,448 | 11 | Columbia Pictures | false | false |
| 20 | - | The Adventures of Milo and Otis | $914,837 | - | 239 | - | $3,827 | $914,837 | 1 | Columbia Pictures | true | false |
| 21 | - | Wired | $869,000 | - | 745 | - | $1,166 | $869,000 | 1 | Taurus Entertainment Company | true | false |
| 22 | - | Cookie | $540,985 | - | 82 | - | $6,597 | $540,985 | 1 | Warner Bros. | true | false |
| 23 | - | Heart of Dixie | $475,752 | - | 359 | - | $1,325 | $475,752 | 1 | Orion Pictures | true | false |
| 24 | - | Little Monsters | $387,881 | - | 179 | - | $2,166 | $387,881 | 1 | United Artists | true | false |
| 25 | - | Romero | $18,827 | - | 2 | - | $9,413 | $18,827 | 1 | Four Square | true | false |
