| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Black Rain | $8,564,334 | -32.7% | 1,610 | - | $5,319 | $21,297,648 | 2 | Paramount Pictures | false | false |
| 2 | 2 | Sea of Love | $7,928,455 | -22.3% | 1,323 | +10 | $5,992 | $31,790,295 | 3 | Universal Pictures | false | false |
| 3 | - | Johnny Handsome | $3,269,584 | - | 812 | - | $4,026 | $3,269,584 | 1 | TriStar Pictures | true | false |
| 4 | 3 | Uncle Buck | $3,251,115 | -16.1% | 1,710 | -74 | $1,901 | $53,758,208 | 7 | Universal Pictures | false | false |
| 5 | 4 | Parenthood | $3,211,931 | -12.9% | 1,366 | -20 | $2,351 | $82,284,594 | 10 | Universal Pictures | false | false |
| 6 | 5 | When Harry Met Sally... | $2,550,173 | -6.7% | 1,162 | -12 | $2,194 | $81,384,385 | 12 | Columbia Pictures | false | false |
| 7 | 8 | Sex, Lies, and Videotape | $1,895,490 | -0.5% | 534 | +13 | $3,549 | $17,700,833 | 9 | Miramax | false | false |
| 8 | 6 | Lethal Weapon 2 | $1,614,188 | -23.5% | 1,131 | -225 | $1,427 | $142,259,912 | 13 | Warner Bros. | false | false |
| 9 | 10 | Turner & Hooch | $1,602,615 | -10.7% | 1,062 | -146 | $1,509 | $65,789,033 | 10 | Walt Disney Studios Motion Pictures | false | false |
| 10 | 7 | The Abyss | $1,547,534 | -20.9% | 1,192 | +16 | $1,298 | $51,702,957 | 8 | Twentieth Century Fox | false | false |
| 11 | 13 | Ghostbusters II | $1,317,571 | +232.2% | 388 | -327 | $3,395 | $112,494,738 | 16 | Columbia Pictures | false | false |
| 12 | 9 | Kickboxer | $1,295,199 | -29.8% | 836 | -127 | $1,549 | $11,712,959 | 4 | Cannon Film Distributors | false | false |
| 13 | 11 | Batman | $1,126,680 | -22.1% | 783 | -232 | $1,438 | $246,141,960 | 15 | Warner Bros. | false | false |
| 14 | 12 | Honey, I Shrunk the Kids | $1,025,397 | -4.9% | 833 | -93 | $1,230 | $124,359,979 | 15 | Walt Disney Studios Motion Pictures | false | false |
| 15 | 15 | Heavy Petting | $39,394 | -62.3% | 11 | +1 | $3,581 | $143,900 | 2 | Skouras Pictures | false | false |
| 16 | - | Thelonious Monk: Straight, No Chaser | $14,965 | - | - | - | - | $14,965 | 1 | Warner Bros. | true | false |
